Evidence map›Paper›PMID 27275614›Full record

ArticleDental press journal of orthodontics

Effect of supplementary zinc on orthodontic tooth movement in a rat model.

Mohammad Sadegh Ahmad Akhoundi, Ahmad Akhoundi Mohammad Sadegh, Rezvaneh Ghazanfari, Ghazanfari Rezvaneh, Shahroo Etemad-Moghadam,, Etemad-Moghadam Shahroo, Mojgan Alaeddini, Alaeddini Mojgan, Azam Khorshidian, Khorshidian Azam and 6 more

Erratum issuedOpen access · diamondAbstract readComparative Study
In one paragraph

Article in Dental press journal of orthodontics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Mohammad Sadegh Ahmad Akhoundi
Ahmad Akhoundi Mohammad Sadegh *Professor, Tehran University of Medical Sciences, Dental Research Center, Orthodontic Department, Tehran, Iran. , Tehran University of Medical Sciences, Tehran University of Medical Sciences, Dental Research Center, Orthodontic Department, Tehran , Iran.
Rezvaneh Ghazanfari
Ghazanfari Rezvaneh *Postgraduate student, Tehran University of Medical Sciences, Prosthodontic Department, Tehran, Iran. , Tehran University of Medical Sciences, Tehran University of Medical Sciences, Prosthodontic Department, Tehran , Iran.
Shahroo Etemad-Moghadam,
Etemad-Moghadam Shahroo *Associate Professor, Tehran University of Medical Sciences, Dental Research Center, Dentistry Research Institute, Tehran, Iran., Tehran University of Medical Sciences, Tehran University of Medical Sciences, Dental Research Center, Dentistry Research Institute, Tehran , Iran.
Mojgan Alaeddini
Alaeddini Mojgan *Associate Professor, Tehran University of Medical Sciences, Dental Research Center, Dentistry Research Institute, Tehran, Iran., Tehran University of Medical Sciences, Tehran University of Medical Sciences, Dental Research Center, Dentistry Research Institute, Tehran , Iran.
Azam Khorshidian
Khorshidian Azam *Dentist, Tehran University of Medical Sciences, Dental Research center, Dentistry Research Institute, Tehran, Iran., Tehran University of Medical Sciences, Tehran University of Medical Sciences, Dental Research center, Dentistry Research Institute, Tehran , Iran.
Shahram Rabbani
Rabbani Shahram *Head of Experimental Research Laboratory, Tehran University of Medical Sciences, Tehran Heart Center, Tehran, Iran., Tehran University of Medical Sciences, Tehran University of Medical Sciences, Tehran Heart Center, Tehran , Iran.
Ahmad Reza Shamshiri
Shamshiri Ahmad Reza *Tehran University of Medical Sciences, Research Center for Caries Prevention, Dentistry Research Institute, Department of Community Oral Health, Tehran, Iran., Tehran University of Medical Sciences, Tehran University of Medical Sciences, Research Center for Caries Prevention, Dentistry Research Institute, Tehran , Iran.
Nafiseh Momeni
Momeni Nafiseh *Dentist, Tehran University of Medical Sciences, Dental Research center, Dentistry Research Institute, Tehran, Iran., Tehran University of Medical Sciences, Tehran University of Medical Sciences, Dental Research center, Dentistry Research Institute, Tehran , Iran.
Tehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOsteoclasts and osteoblasts are responsible for regulating bone homeostasis during which the trace element zinc has been shown to exert a cumulative effect on bone mass by stimulating osteoblastic bone formation and inhibiting osteoclastic bone resorption.

objectiveThe aim of the present study was to investigate the effects of zinc (Zn) on orthodontic tooth movement (OTM) in a rat model. MATERIAL AND

methodsA total of 44 male Wistar rats were divided into four groups of 11 animals each and received 0, 1.5, 20 and 50 ppm Zn in distilled water for 60 days. In the last 21 days of the study, nickel-titanium closed coil springs were ligated between maxillary right incisors and first molars of all rats, and tooth movement was measured at the end of this period. Histological analysis of hematoxylin/eosin slides was performed to assess root resorption lacunae, osteoclast number and periodontal ligament (PDL) width.

resultsMean OTM was calculated as 51.8, 49.1, 35.5 and 45 µm in the 0, 1.5, 20 and 50 ppm zinc-receiving groups, respectively. There were no significant differences in neither OTM nor histological parameters among the study groups (p > 0.05).

conclusionAccording to the results obtained in the current investigation, increase in supplementary zinc up to 50 ppm does not affect the rate of OTM neither bone and root resorption in rats.

Indexed as

AnimalsBone ResorptionDose-Response Relationship, DrugMaleOsteoblastsPeriodontal LigamentRatsRats, WistarTooth Movement TechniquesZincZinc

Identifiers

PMID27275614
PMCPMC4896281
OpenAlexW2470698438

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.