Evidence map›Paper›PMID 27275585›Full record

ReviewEuropean journal of pain (London, England)2016

Post-traumatic stress symptoms in children and adolescents with chronic pain: A topical review of the literature and a proposed framework for future research.

A L Holley, A C Wilson, M Noel, T M Palermo

Open access · greenAbstract readReview
In one paragraph

Review in European journal of pain (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
19.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 98 citations in OpenAlex.

  1. Pooled it
  2. Hospital experiences and medical traumatic stress in adults with spina bifida.Journal of pediatric rehabilitation medicine · 2025
    Article
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  5. Chronic pain in transgender and gender-diverse youth: a biopsychosocial perspective.Frontiers in pain research (Lausanne, Switzerland) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

A L HolleyDivision of Psychology, Oregon Health & Science University, Portland, USA. holleya@ohsu.edu.
A C WilsonDivision of Psychology, Oregon Health & Science University, Portland, USA.
M NoelDepartment of Psychology, University of Calgary and Alberta Children's Hospital Research Institute, AB, Canada.
T M PalermoDepartment of Anesthesiology and Pain Medicine, University of Washington and Seattle Children's Research Institute, USA.
Oregon Health & Science University · USAlberta Children's Hospital · CAUniversity of Washington · US

Funding

Innovations in Pediatric Pain ResearchK24HD060068 · NICHD · SEATTLE CHILDREN'S HOSPITAL · PI PALERMO, TONYA M · 2009 to 2018
$1.6M
Chronic Pain in Pediatric Primary CareK23HD071946 · NICHD · SEATTLE CHILDREN'S HOSPITAL · PI LEWANDOWSKI HOLLEY, AMY S · 2012 to 2016
$583k
Adolescents at risk for chronic painK23HD064705 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI WILSON, ANNA CAMILLE · 2010 to 2014
$539k
CIHRNICHD NIH HHS K23 HD064705NICHD NIH HHS K23 HD071946NICHD NIH HHS K24 HD060068
6 · The paper itself

Abstract

BACKGROUND AND

objectiveThe co-occurrence of chronic pain and post-traumatic stress symptoms (PTSS) and post-traumatic stress disorder (PTSD) has gained increasing research attention. Studies on associations among pain and PTSS or PTSD in youth have largely been conducted in the context of acute injury or trauma. Less is known about the risk for co-occurrence with paediatric chronic pain. In this review, we (1) propose a conceptual framework to outline factors salient during childhood that may be associated with symptom severity, co-occurrence and mutual maintenance, (2) present relevant literature on PTSS in youth with acute and chronic pain and identify research gaps and (3) provide recommendations to guide paediatric research examining shared symptomatology. DATABASES AND DATA TREATMENT: Electronic databases (PubMed and Google Scholar) were used to identify relevant articles using the search terms 'child, adolescent, paediatric, chronic pain, acute pain, post-traumatic stress symptoms and post-traumatic stress disorder'. Studies were retrieved and reviewed based on relevance to the topic.

resultsOur findings revealed that existing biobehavioural and ecological models of paediatric chronic pain lack attention to traumatic events or the potential development of PTSS. Paediatric studies are also limited by lack of a conceptual framework for understanding the prevalence, risk and trajectories of PTSS in youth with chronic pain.

conclusionsOur new developmentally informed framework highlights individual symptoms and shared contextual factors that are important when examining potential associations among paediatric chronic pain and PTSS. Future studies should consider bidirectional and mutually maintaining associations, which will be aided by prospective, longitudinal designs. WHAT DOES THIS REVIEW ADD?: This review presents relevant literature on pain and PTSS in youth and proposes a conceptual framework to examine factors salient during childhood that may be associated with symptom severity, comorbidity and mutual maintenance of chronic pain and PTSS in paediatric populations. We highlight dynamic factors that may change across children's development and provide recommendations to guide paediatric research examining potential associations among PTSS and chronic pain.

Indexed as

AdolescentChildChronic PainComorbidityFemaleHumansMalePrevalenceProspective StudiesResearchStress Disorders, Post-Traumatic

Identifiers

PMID27275585
PMCPMC5912261
OpenAlexW2409031685

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.