Evidence map›Paper›PMID 27275457›Full record

ArticleCase reports in nephrology and dialysis

Acute Respiratory Distress Syndrome and Posterior Reversible Encephalopathy Syndrome following Rituximab Therapy.

Katrina E Wardrope, Lynn Manson, Wendy Metcalfe, Eoin D O Sullivan

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in nephrology and dialysis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Katrina E WardropeDepartment of Renal Medicine, Royal Infirmary of Edinburgh, Edinburgh, UK.
Lynn MansonScottish National Blood Transfusion Service, Edinburgh, UK.
Wendy MetcalfeDepartment of Renal Medicine, Royal Infirmary of Edinburgh, Edinburgh, UK.
Eoin D O SullivanDepartment of Renal Medicine, Royal Infirmary of Edinburgh, Edinburgh, UK.
Edinburgh Royal Infirmary · GBScottish National Blood Transfusion Service · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The anti-CD20 monoclonal antibody rituximab is associated with rare but significant adverse events, notably posterior reversible encephalopathy syndrome (PRES) and acute respiratory distress syndrome (ARDS). We report a case of concomitant ARDS and PRES developing after rituximab therapy for treatment of cryoglobulinaemic vasculitis. There are 7 reported cases of PRES complicating rituximab use. PRES onset varied from immediate to 21 days after administration. All patients recovered completely, and rituximab was reintroduced in half of the cases. The occurrence of ARDS in association with rituximab is rarer. Only 3 confirmed cases exist, and ARDS may occur as a delayed reaction.

Indexed as

Acute respiratory distress syndromeCryoglobulinaemiaPosterior reversible encephalopathy syndromeRituximab

Identifiers

PMID27275457
PMCPMC4886031
OpenAlexW2273851380

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.