Evidence map›Paper›PMID 27275439›Full record

ReviewInternational journal of ophthalmology2016

Ocular diseases: immunological and molecular mechanisms.

Jing Song, Yi-Fei Huang, Wen-Jing Zhang, Xiao-Fei Chen, Yu-Mian Guo

Abstract readReview
In one paragraph

Review in International journal of ophthalmology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Advances in the molecular pathogenesis ofFrontiers in cellular and infection microbiology · 2026
    Review
  2. Review
  3. Article
  4. Review
  5. Precision genome editing in the eye.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  6. Article
  7. Comparative profile of ocular surface microbiome in vernal keratoconjunctivitis patients and healthy subjects.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jing SongDepartment of Ophthalmology, Affiliated Hospital of Logistics University of People's Armed Police Force, Tianjin 300161, China.
Yi-Fei HuangDepartment of Ophthalmology, Affiliated Hospital of Logistics University of People's Armed Police Force, Tianjin 300161, China; Department of Ophthalmology, General Hospital of PLA, Beijing 100853, China.
Wen-Jing ZhangDepartment of Ophthalmology, Affiliated Hospital of Logistics University of People's Armed Police Force, Tianjin 300161, China.
Xiao-Fei ChenDepartment of Ophthalmology, General Hospital of PLA, Beijing 100853, China.
Yu-Mian GuoDepartment of Ophthalmology, Affiliated Hospital of Logistics University of People's Armed Police Force, Tianjin 300161, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many factors, such as environmental, microbial and endogenous stress, antigen localization, can trigger the immunological events that affect the ending of the diverse spectrum of ocular disorders. Significant advances in understanding of immunological and molecular mechanisms have been researched to improve the diagnosis and therapy for patients with ocular inflammatory diseases. Some kinds of ocular diseases are inadequately responsive to current medications; therefore, immunotherapy may be a potential choice as an alternative or adjunctive treatment, even in the prophylactic setting. This article first provides an overview of the immunological and molecular mechanisms concerning several typical and common ocular diseases; second, the functions of immunological roles in some of systemic autoimmunity will be discussed; third, we will provide a summary of the mechanisms that dictate immune cell trafficking to ocular local microenvironment in response to inflammation.

Indexed as

chemokinesimmune responseimmunological mechanismocular diseasessystemic autoimmunity

Identifiers

PMID27275439
PMCPMC4886870

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.