Evidence map›Paper›PMID 27275130›Full record

ArticleInternational journal of mass spectrometry2015

Investigation of the Mechanism of Electron Capture and Electron Transfer Dissociation of Peptides with a Covalently Attached Free Radical Hydrogen Atom Scavenger.

Chang Ho Sohn, Sheng Yin, Ivory Peng, Joseph A Loo, J L Beauchamp

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of mass spectrometry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 11 citations in OpenAlex.

  1. Replacing HChemical science · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Chang Ho SohnDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125.
Sheng YinDepartment of Chemistry and Biochemistry, University of California, Los Angeles, California 90095.
Ivory PengDepartment of Chemistry and Biochemistry, University of California, Los Angeles, California 90095.
Joseph A LooDepartment of Chemistry and Biochemistry, University of California, Los Angeles, California 90095; Department of Biological Chemistry, David Geffen School of Medicine at UCLA, University of California, Los Angeles, California 90095; UCLA/DOE Institute of Genomics and Proteomics, University of California, Los Angeles, California 90095.
J L BeauchampDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125.
University of California, Los Angeles · USCalifornia Institute of Technology · US

Funding

UV Laser for Photodissociation-Mass Spectrometry of Proteins and Protein ComplexesR01GM103479 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LOO, JOSEPH A · 2012 to 2021
$3.2M
High Resolution Hybrid FT-ICR Mass SpectrometerS10RR023045 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LOO, JOSEPH A · 2006 to 2006
$1.2M
NCRR NIH HHS S10 RR023045NIGMS NIH HHS R01 GM103479
6 · The paper itself

Abstract

The mechanisms of electron capture and electron transfer dissociation (ECD and ETD) are investigated by covalently attaching a free-radical hydrogen atom scavenger to a peptide. The 2,2,6,6-tetramethylpiperidin-l-oxyl (TEMPO) radical was chosen as the scavenger due to its high hydrogen atom affinity (ca. 280 kJ/mol) and low electron affinity (ca. 0.45 ev), and was derivatized to the model peptide, FQX

Indexed as

Electron Capture DissociationElectron Transfer DissociationFree RadicalPeptideReaction MechanismTEMPO

Identifiers

PMID27275130
PMCPMC4892187
OpenAlexW1759052172

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.