ArticleWorld journal of gastroenterology2016
Blood neutrophil-lymphocyte ratio predicts survival after hepatectomy for hepatocellular carcinoma: A propensity score-based analysis.
Article in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Neutrophil to lymphocyte ratio and albumin bilirubin grade in hepatocellular carcinoma: A systematic review.World journal of gastroenterology · 2020Pooled it
- AGLR is a novel index for the prognosis of hepatocellular carcinoma patients: a retrospective study.BMC surgery · 2021Trial
- Predicting lymph node metastasis using preoperative parameters in patients with T1 ampulla of vater cancer.BMC cancer · 2024Article
- Review
- Multisequence MRI-Based Radiomic Features Combined with Inflammatory Indices for Predicting the Overall Survival of HCC Patients After TACE.Journal of hepatocellular carcinoma · 2024Article
- Interleukin-8 is superior to CRP for the prediction of severe complications in a prospective cohort of patients undergoing major liver resection.Langenbeck's archives of surgery · 2023Article
- Preoperative inflammatory markers as prognostic predictors after hepatocellular carcinoma resection: data from a western referral center.BMC surgery · 2022Article
- Novel combined fibrosis-based index predicts the long-term outcomes of hepatocellular carcinoma after hepatic resection.International journal of clinical oncology · 2022Article
- Article
- Phase Attention Model for Prediction of Early Recurrence of Hepatocellular Carcinoma With Multi-Phase CT Images and Clinical Data.Frontiers in radiology · 2022Article
- Neutrophil Lymphocyte Ratio to Albumin Ratio and White Blood Cell to Hemoglobin Ratio as Prognostic Markers for Hepatocellular Carcinoma Patients Who Underwent Curative Hepatectomy.International journal of general medicine · 2021Article
- Prognostic effect of preoperative neutrophil-lymphocyte ratio is related with tumor necrosis and tumor-infiltrating lymphocytes in hepatocellular carcinoma.Virchows Archiv : an international journal of pathology · 2020Article
- Higher neutrophil-lymphocyte ratio is associated with better prognosis of hepatocellular carcinoma.Medicine · 2020Article
- Underlying liver disease and advanced stage liver cancer are associated with elevated neutrophil-lymphocyte ratio.Clinical and molecular hepatology · 2019Article
- The prognostic significance of the neutrophil-to-lymphocyte ratio and the platelet-to-lymphocyte ratio in giant cell tumor of the extremities.BMC cancer · 2019Article
- Analysis of Clinical Characteristics and Poor Prognostic Predictors in Patients With an Initial Diagnosis of Autoimmune Encephalitis.Frontiers in immunology · 2019Article
- The lymphocyte-to-monocyte ratio is a superior predictor of overall survival compared to established biomarkers in HCC patients undergoing liver resection.Scientific reports · 2018Article
- Prognostic nomogram for hepatocellular carcinoma in adolescent and young adult patients after hepatectomy.Oncotarget · 2017Article
- Neutrophil to lymphocyte ratio may be a helpful marker to evaluate disease activity in NMOSD.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2017Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate whether an elevated preoperative neutrophil-to-lymphocyte ratio (NLR) can predict poor survival in patients with hepatocellular carcinoma (HCC).
methodsWe retrospectively reviewed 526 patients with HCC who underwent surgery between 2004 and 2011.
resultsPreoperative NLR ≥ 2.81 was an independent predictor of poor disease-free survival (DFS, P < 0.001) and overall survival (OS, P = 0.044). Compared with patients who showed a preoperative NLR < 2.81 and postoperative increase, patients who showed preoperative NLR ≥ 2.81 and postoperative decrease had worse survival (DFS, P < 0.001; OS, P < 0.001). Among patients with preoperative NLR ≥ 2.81, survival was significantly higher among those showing a postoperative decrease in NLR than among those showing an increase (DFS, P < 0.001; OS, P < 0.001). When elevated, alpha-fetoprotein (AFP) provided no prognostic information, and so preoperative NLR ≥ 2.81 may be a good complementary indicator of poor OS whenever AFP levels are low or high.
conclusionPreoperative NLR ≥ 2.81 may be an indicator of poor DFS and OS in patients with HCC undergoing surgery. Preoperative NLR ≥ 2.81 may be a good complementary indicator of poor OS when elevated AFP levels provide no prognostic information.
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