ArticleJournal of anaesthesiology, clinical pharmacology
Postoperative analgesia in children: A comparison of three different doses of caudal epidural morphine.
Article in Journal of anaesthesiology, clinical pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06846983 (Peripheral Perfusion Index as an Early Predictor of Successful Caudal Block in Pediatric Patients Undergoing Lower Abdominopelvic Surgeries Under General Anesthesia), which is not on this map. Cited by 8 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Peripheral Perfusion Index as an Early Predictor of Successful Caudal Block in Pediatric Patients Undergoing Lower Abdominopelvic Surgeries Under General Anesthesia
Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- Assessment of stress response attenuation with caudal morphine using a surrogate marker during pediatric cardiac surgery.Annals of cardiac anaesthesiaTrial
- Efficacy and safety of paravertebral blockade in paediatric cardiothoracic surgery: a protocol for systematic review and meta-analysis.BMJ open · 2025Article
- Methods of prolonging the effect of caudal block in children.Frontiers in pediatrics · 2024Review
- Caudal catheter placement for repeated epidural morphine doses after neonatal upper abdominal surgery.Anaesthesia and intensive care · 2022Article
- Postoperative Pain Management: Efficacy of Caudal Tramadol in Pediatric Lower Abdominal Surgery: A Randomized Clinical Study.Anesthesiology and pain medicine · 2021Article
- [Stocktaking of local anesthetics 2020].Der Anaesthesist · 2020Review
- Perfusion index as a predictor of working pediatric caudal block under general anesthesia- A prospective observational study.Journal of anaesthesiology, clinical pharmacologyArticle
- Perfusion index as primary predictor of successful caudal block in infraumbilical and lower limb pediatric surgeries: A prospective observational study.Saudi journal of anaesthesiaArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsCaudal epidural block is the most commonly used neuraxial block in children. Morphine has been used as a caudal additive for more than three decades. The aim of our study was to evaluate the efficacy and duration of analgesia of three different doses of caudal epidural morphine (CEM), and to find out the incidence of side effects. MATERIAL AND
methodsThis study was conducted on 75 patients of American Society of Anesthesiologists grades I and II, aged 2-12 years, undergoing lower abdominal and urogenital surgeries. Patients were randomly allocated to one of the three groups according to the dose of morphine. Group I received 30 μg/kg, group II 50 μg/kg, and group III 70 μg/kg. Heart rate, blood pressure, oxygen saturation, electrocardiogram, pain score, sedation score, duration of analgesia, and side-effects were noted.
resultsThe mean duration of analgesia was 8.63 h in group I, 13.36 h in group II and 19.19 h in group III. Respiratory depression was noted in three patients in group III. One patient in group I had itching. One patient each in groups I, II, and III had nausea/vomiting.
conclusionCEM significantly prolongs the duration of analgesia, though with a higher dose the risk of respiratory depression should always be kept in mind.
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