Evidence map›Paper›PMID 27275015›Full record

ArticleJCI insight2016

Abnormal

Keisuke Maeshima, Stephanie M Stanford, Deepa Hammaker, Cristiano Sacchetti, Li-Fan Zeng, Rizi Ai, Vida Zhang, David L Boyle, German R Aleman Muench, Gen-Sheng Feng and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JCI insight, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Protein phosphatases in systemic autoimmunity.Immunometabolism (Cobham, Surrey) · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. From Stem to Sternum: The Role of Shp2 in the Skeleton.Calcified tissue international · 2023
    Review
  12. Review
  13. Mitogen-Activated Protein Kinase Phosphatases: No Longer Undruggable?Annual review of pharmacology and toxicology · 2023
    Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Keisuke MaeshimaDivision of Rheumatology, Allergy and Immunology, University of California, San Diego School of Medicine, La Jolla, California, USA.
Stephanie M StanfordDivision of Cellular Biology, La Jolla Institute for Allergy and Immunology, La Jolla, California, USA.
Deepa HammakerDivision of Rheumatology, Allergy and Immunology, University of California, San Diego School of Medicine, La Jolla, California, USA.
Cristiano SacchettiDivision of Cellular Biology, La Jolla Institute for Allergy and Immunology, La Jolla, California, USA.
Li-Fan ZengDepartment of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Rizi AiDepartment of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California, USA.
Vida ZhangDivision of Cellular Biology, La Jolla Institute for Allergy and Immunology, La Jolla, California, USA.
David L BoyleDivision of Rheumatology, Allergy and Immunology, University of California, San Diego School of Medicine, La Jolla, California, USA.
German R Aleman MuenchDivision of Cellular Biology, La Jolla Institute for Allergy and Immunology, La Jolla, California, USA.
Gen-Sheng FengDepartment of Pathology and Division of Biological Sciences, University of California, San Diego, La Jolla, California, USA.
John W WhitakerJanssen Pharmaceuticals Companies of Johnson and Johnson, La Jolla, California, USA.
Zhong-Yin ZhangDepartment of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Wei WangDepartment of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California, USA.
Nunzio BottiniDivision of Rheumatology, Allergy and Immunology, University of California, San Diego School of Medicine, La Jolla, California, USA.; Division of Cellular Biology, La Jolla Institute for Allergy and Immunology, La Jolla, California, USA.
Gary S FiresteinDivision of Rheumatology, Allergy and Immunology, University of California, San Diego School of Medicine, La Jolla, California, USA.
University of California, San Diego · USLa Jolla Institute for Immunology · USIndiana University – Purdue University Indianapolis · USIndiana University School of Medicine

Funding

Structure/Function of Protein Tyrosine PhosphatasesR01CA069202 · NCI · YESHIVA UNIVERSITY · PI Zhong-Yin Zhang · 1996 to 2026
$7.3M
Identification of key regulators in rheumatoid arthritisR01AR065466 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, WANG, WEI · 2014 to 2024
$4.6M
Role of PTPRS in Rheumatoid ArtiritisR01AR066053 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BOTTINI, NUNZIO · 2014 to 2025
$4.0M
Dissection of Pten-regulated signals in hepatopathogenesisR01CA188506 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FENG, GEN-SHENG · 2015 to 2019
$1.9M
Molecular and Cellular Communications in Liver TumorigenesisR01CA176012 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FENG, GEN-SHENG · 2014 to 2019
$1.7M
Shp2 and Pten in Leukemia and AnemiaR01HL129763 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FENG, GEN-SHENG · 2015 to 2018
$1.6M
NCI NIH HHS R01 CA069202NCI NIH HHS R01 CA176012NCI NIH HHS R01 CA188506NHLBI NIH HHS R01 HL129763NIAMS NIH HHS R01 AR065466NIAMS NIH HHS R01 AR066053
6 · The paper itself

Abstract

The

Identifiers

PMID27275015
PMCPMC4889026
OpenAlexW2406712460

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.