Evidence map›Paper›PMID 27274811›Full record

ArticleToxicology research2016

Absence of Cytotoxicity towards Microglia of Iron Oxide (α-Fe

Crystal S Lewis, Luisa Torres, Jeremy T Miyauchi, Cyrus Rastegar, Jonathan M Patete, Jacqueline M Smith, Stanislaus S Wong, Stella E Tsirka

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Multimodal microscopic and spectroscopic characterisation of heterogeneous iron oxyhydroxides in the human globus pallidus.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
  2. Article
  3. Review
  4. Magnetic iron oxide nanoparticles for imaging, targeting and treatment of primary and metastatic tumors of the brain.Journal of controlled release : official journal of the Controlled Release Society · 2020
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Crystal S LewisDepartment of Chemistry, State University of New York at Stony Brook, Stony Brook,New York 11794-3400, USA.
Luisa TorresDepartment of Pharmacological Sciences, State University of New York at Stony Brook, Stony Brook, New York 11794-8651, USA.
Jeremy T MiyauchiDepartment of Pharmacological Sciences, State University of New York at Stony Brook, Stony Brook, New York 11794-8651, USA.
Cyrus RastegarDepartment of Pharmacological Sciences, State University of New York at Stony Brook, Stony Brook, New York 11794-8651, USA.
Jonathan M PateteDepartment of Chemistry, State University of New York at Stony Brook, Stony Brook,New York 11794-3400, USA.
Jacqueline M SmithDepartment of Chemistry, State University of New York at Stony Brook, Stony Brook,New York 11794-3400, USA.
Stanislaus S WongDepartment of Chemistry, State University of New York at Stony Brook, Stony Brook,New York 11794-3400, USA; Condensed Matter Physics and Materials Science Department, Building 480, Brookhaven National Laboratory, Upton, New York 11973, USA.
Stella E TsirkaDepartment of Pharmacological Sciences, State University of New York at Stony Brook, Stony Brook, New York 11794-8651, USA.
Stony Brook University · USState University of New York · US

Funding

Training Program in Pharmacological SciencesT32GM007518 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI GARCIA-DIAZ, MIGUEL · 1985 to 2021
$5.4M
Microglial effector pathways in the CNSR01NS042168 · NINDS · STATE UNIVERSITY NEW YORK STONY BROOK · PI TSIRKA, STYLIANI-ANNA (STELLA) E · 2003 to 2011
$3.1M
The role of Neuropilin 1 in Glioma Associated Microglia and MacrophagesF30CA196110 · NCI · STATE UNIVERSITY NEW YORK STONY BROOK · PI MIYAUCHI, JEREMY TETSUO · 2016 to 2019
$147k
NCI NIH HHS F30 CA196110NIGMS NIH HHS T32 GM007518NINDS NIH HHS R01 NS042168
6 · The paper itself

Abstract

Understanding the nature of interactions between nanomaterials, such as commercially ubiquitous hematite (α-Fe

Indexed as

CytotoxicityMicrogliaNeurotoxicityα-Fe2O3 nanostructures

Identifiers

PMID27274811
PMCPMC4890976
OpenAlexW2283714226

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.