ArticleNutrition & metabolism2016
Association of low oleic acid intake with diabetic retinopathy in type 2 diabetic patients: a case-control study.
Article in Nutrition & metabolism, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Pooled it
- Diet and risk of diabetic retinopathy: a systematic review.European journal of epidemiology · 2018Pooled it
- Pooled it
- Trial
- Metabolic Dysfunction and Inflammation in Diabetic Retinopathy: Insights From Metabolomics and Cytokine Analysis.Mediators of inflammation · 2026Article
- Heterogeneous impacts of carbohydrate subtypes on the progression of microvascular complications in hyperglycemic individuals: evidence from the UK biobank.Nutrition journal · 2025Article
- Association between dietary niacin intake and diabetic retinopathy in a Catalonian population: a cross-sectional study.Frontiers in nutrition · 2025Article
- The Role of Diet and Oral Supplementation for the Management of Diabetic Retinopathy and Diabetic Macular Edema: A Narrative Review.BioMed research international · 2025Review
- Deciphering the role of oleic acid in diabetic retinopathy: an empirical analysis of monounsaturated fatty acids.Nutrition & metabolism · 2024Article
- Metabolites as Risk Factors for Diabetic Retinopathy in Patients With Type 2 Diabetes: A 12-Year Follow-up Study.The Journal of clinical endocrinology and metabolism · 2023Article
- Associations between fatty acid intake and diabetic retinopathy in a Japanese population.Scientific reports · 2023Article
- A Mediterranean Diet May Be Protective in the Development of Diabetic Retinopathy.International journal of molecular sciences · 2023Review
- Diabetic retinopathy as the leading cause of blindness and early predictor of cascading complications-risks and mitigation.The EPMA journal · 2023Review
- Certain Dietary Nutrients Reduce the Risk of Eye Affliction/Retinopathy in Individuals with Diabetes: National Health and Nutrition Examination Survey, 2003-2018.International journal of environmental research and public health · 2022Article
- The Effect of Hyperlipidemia on the Course of Diabetic Retinopathy-Literature Review.Journal of clinical medicine · 2022Review
- The Effect of Diet and Lifestyle on the Course of Diabetic Retinopathy-A Review of the Literature.Nutrients · 2022Review
- Impacts of high fat diet on ocular outcomes in rodent models of visual disease.Experimental eye research · 2021Review
- Type 1 Diabetic Subjects with Diabetic Retinopathy Show an Unfavorable Pattern of Fat Intake.Nutrients · 2018Article
- INCREASED DIETARY INTAKE AND SERUM LEVELS OF ADVANCED GLYCATION END PRODUCTS (AGES) ARE ASSOCIATED WITH DIABETIC MACULAR EDEMA.Acta endocrinologica (Bucharest, Romania : 2005)Article
Corrections and comments
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Authors and funding
15 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe objective of this study was to describe the intake of macronutrient, especially fatty acids, and explore their possible effect on diabetic retinopathy (DR) in patients with type 2 diabetes mellitus.
methodsIn this case-control study, we included a total of 146 patients with DR and 148 without DR. The intake of macronutrient was evaluated using a validated food frequency questionnaire. We used logistic regression adjusted for sex, age, diabetes duration, energy intake, educational level, physical activity, waist circumference, systolic blood pressure, high-density lipoprotein cholesterol and diabetes treatment, to estimate odds ratio (ORs) of DR.
resultsPatients with DR had significantly lower intake of fibre, monounsaturated fatty acids (MUFA), and palmitic and oleic acid. Inverse associations were observed between MUFA and oleic acid intake in DR. Subjects with intermediate and high MUFA intake were less likely to have DR than those with lower MUFA intake, with ORs of 0.46 (95 % CI: 0.22-0.93) and 0.42 (95 % CI: 0.18-0.97), respectively. Similarly, intermediate and high oleic acid intake were associated with reduced DR frequency compared with low oleic acid intake, with OR values of 0.48 (95 % CI: 0.23-0.97) and 0.37 (95 % CI: 0.16-0.85), respectively. These associations were stronger in patients with a longer diabetes duration.
conclusionIn type 2 diabetes mellitus, MUFA and oleic acid intake were inversely associated with DR.
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Registered trials
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