Evidence map›Paper›PMID 27274751›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2016

Prevention and Therapeutic Effects and Mechanisms of Tanshinone IIA Sodium Sulfonate on Acute Liver Injury Mice Model.

Lunjie Lu, Jun Zhou, Jingying Zhang, Jun Che, Yang Jiao, Yusong Zhang

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Lunjie LuDepartment of Oncology, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China; Department of Radiation Genetics, School of Radiation Medicine and Protection, Soochow University School of Medicine, Suzhou 215123, China.
Jun ZhouDepartment of Emergency, Suzhou Kowloon Hospital, Shanghai Jiao Tong University School of Medicine, Suzhou 215000, China.
Jingying ZhangDepartment of Radiation Genetics, School of Radiation Medicine and Protection, Soochow University School of Medicine, Suzhou 215123, China.
Jun CheDepartment of Radiation Oncology, The Affiliated Hospital of Jiangnan University, Wuxi 214062, China.
Yang JiaoDepartment of Radiation Genetics, School of Radiation Medicine and Protection, Soochow University School of Medicine, Suzhou 215123, China.
Yusong ZhangDepartment of Oncology, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
Soochow University · CNJiangnan University · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tanshinone IIA sodium sulfonate (TSS) is a water-soluble derivative of tanshinone IIA, which is the main pharmacologically active component of Salvia miltiorrhiza. This study aimed to verify the preventive and therapeutic effects of TSS and its combined therapeutic effects with magnesium isoglycyrrhizinate (MI) in D-galactosamine- (D-Gal-) induced acute liver injury (ALI) in mice. The potential regulatory mechanisms of TSS on ALI were also examined. Our results may provide a basis for the development of novel therapeutics for ALI.

Identifiers

PMID27274751
PMCPMC4870345
OpenAlexW2346083246

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.