ReviewMedical devices (Auckland, N.Z.)2016
The activL(®) Artificial Disc: a next-generation motion-preserving implant for chronic lumbar discogenic pain.
Review in Medical devices (Auckland, N.Z.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 18 citations in OpenAlex.
- A Comprehensive Review of Spinal Arthroplasty.Neurospine · 2026Review
- Towards biomimetic evolution of artificial intervertebral disc: a review.Medical & biological engineering & computing · 2025Review
- The Decline of Lumbar Artificial Disc Replacement.Journal of spine research and surgery · 2024Article
- Single-Level Total Disc Replacement: Mid- to Long-Term Outcomes.International journal of spine surgery · 2022Article
- Cervical and Lumbar Disc Arthroplasty: A Review of Current Implant Design and Outcomes.Bioengineering (Basel, Switzerland) · 2022Review
- Final Long-Term Reporting from a Randomized Controlled IDE Trial for Lumbar Artificial Discs in Single-Level Degenerative Disc Disease: 7-Year Results.International journal of spine surgery · 2021Article
- 2021 Position Statement From the International Society for the Advancement of Spine Surgery on Cervical and Lumbar Disc Replacement.International journal of spine surgery · 2021Article
- 3D Bioprinted Implants for Cartilage Repair in Intervertebral Discs and Knee Menisci.Frontiers in bioengineering and biotechnology · 2021Review
- [A review on the current state of ball-on-socket type artificial lumbar disc prosthesis].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2020Review
- Comparison of Lumbar Total Disc Replacement With Surgical Spinal Fusion for the Treatment of Single-Level Degenerative Disc Disease: A Meta-Analysis of 5-Year Outcomes From Randomized Controlled Trials.Global spine journal · 2018Review
- We Need to Talk about Lumbar Total Disc Replacement.International journal of spine surgery · 2018Article
- Lumbar disc replacement surgery-successes and obstacles to widespread adoption.Current reviews in musculoskeletal medicine · 2017Review
- Preserving spinal motion: lumbar disc arthroplasty in the US.Current orthopaedic practiceReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Degeneration of the lumbar intervertebral discs is a leading cause of chronic low back pain in adults. Treatment options for patients with chronic lumbar discogenic pain unresponsive to conservative management include total disc replacement (TDR) or lumbar fusion. Until recently, only two lumbar TDRs had been approved by the US Food and Drug Administration - the Charité Artificial Disc in 2004 and the ProDisc-L Total Disc Replacement in 2006. In June 2015, a next-generation lumbar TDR received Food and Drug Administration approval - the activL(®) Artificial Disc (Aesculap Implant Systems). Compared to previous-generation lumbar TDRs, the activL(®) Artificial Disc incorporates specific design enhancements that result in a more precise anatomical match and allow a range of motion that better mimics the healthy spine. The results of mechanical and clinical studies demonstrate that the activL(®) Artificial Disc results in improved mechanical and clinical outcomes versus earlier-generation artificial discs and compares favorably to lumbar fusion. The purpose of this report is to describe the activL(®) Artificial Disc including implant characteristics, intended use, surgical technique, postoperative care, mechanical testing, and clinical experience to date.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.