Evidence map›Paper›PMID 27274238›Full record

ReviewInternational journal of nanomedicine2016

Current status and perspectives in atomic force microscopy-based identification of cellular transformation.

Chenbo Dong, Xiao Hu, Cerasela Zoica Dinu

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Mechanical Modulation of Ovarian Cancer Tumor Nodules Under Flow.IEEE transactions on bio-medical engineering · 2022
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chenbo DongDepartment of Chemical and Biomedical Engineering, West Virginia University, Morgantown, WV, USA.
Xiao HuDepartment of Chemical and Biomedical Engineering, West Virginia University, Morgantown, WV, USA.
Cerasela Zoica DinuDepartment of Chemical and Biomedical Engineering, West Virginia University, Morgantown, WV, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the complex interplay between cells and their biomechanics and how the interplay is influenced by the extracellular microenvironment, as well as how the transforming potential of a tissue from a benign to a cancerous one is related to the dynamics of both the cell and its surroundings, holds promise for the development of targeted translational therapies. This review provides a comprehensive overview of atomic force microscopy-based technology and its applications for identification of cellular progression to a cancerous phenotype. The review also offers insights into the advancements that are required for the next user-controlled tool to allow for the identification of early cell transformation and thus potentially lead to improved therapeutic outcomes.

Indexed as

Biomechanical PhenomenaCell Transformation, NeoplasticHumansMicroscopy, Atomic ForceNeoplasmsPrecancerous Conditionsatomic force microscopy (AFM)bio-nano-mechanical signaturecancerous phenotypemalignant transformationnanoindentation

Identifiers

PMID27274238
PMCPMC4876801

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.