Evidence map›Paper›PMID 27274212›Full record

Observational studyClinical interventions in aging2016

Fraction of exhaled nitric oxide measurements in the diagnoses of asthma in elderly patients.

Antonio Carlos Maneira Godinho Netto, Túlio Gonçalves Dos Reis, Cássia Franco Matheus, Beatriz Julião Vieira Aarestrup, Fernando Monteiro Aarestrup

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Clinical interventions in aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Asthma Over the Age of 65: All's Well That Ends Well.The journal of allergy and clinical immunology. In practice
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Antonio Carlos Maneira Godinho NettoSchool of Medical and Health Sciences - SUPREMA, Federal University of Juiz de Fora, Institute of Biological Sciences, Juiz de Fora, Brazil; Maternity Hospital Terezinha de Jesus, Federal University of Juiz de Fora, Institute of Biological Sciences, Juiz de Fora, Brazil.
Túlio Gonçalves Dos ReisSchool of Medical and Health Sciences - SUPREMA, Federal University of Juiz de Fora, Institute of Biological Sciences, Juiz de Fora, Brazil; Maternity Hospital Terezinha de Jesus, Federal University of Juiz de Fora, Institute of Biological Sciences, Juiz de Fora, Brazil.
Cássia Franco MatheusSchool of Medical and Health Sciences - SUPREMA, Federal University of Juiz de Fora, Institute of Biological Sciences, Juiz de Fora, Brazil; Maternity Hospital Terezinha de Jesus, Federal University of Juiz de Fora, Institute of Biological Sciences, Juiz de Fora, Brazil.
Beatriz Julião Vieira AarestrupMorphology Department, Federal University of Juiz de Fora, Institute of Biological Sciences, Juiz de Fora, Brazil; Laboratory of Immunopathology and Experimental Pathology, Federal University of Juiz de Fora, Reproductive Biology Center (CBR), Juiz de Fora, Brazil.
Fernando Monteiro AarestrupSchool of Medical and Health Sciences - SUPREMA, Federal University of Juiz de Fora, Institute of Biological Sciences, Juiz de Fora, Brazil; Maternity Hospital Terezinha de Jesus, Federal University of Juiz de Fora, Institute of Biological Sciences, Juiz de Fora, Brazil; Laboratory of Immunopathology and Experimental Pathology, Federal University of Juiz de Fora, Reproductive Biology Center (CBR), Juiz de Fora, Brazil.
Universidade Federal de Juiz de Fora · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the value of fraction of exhaled nitric oxide (FeNO) measurements in the diagnosis of asthma in elderly patients.

methodsThe clinical symptoms of 202 elderly patients were assessed with the asthma module of the International Study of Asthma and Allergies in Childhood test, which had been modified for the elderly patients, and the diagnostic routine for chronic obstructive pulmonary disease (COPD), which was based on the Global initiative for chronic Obstructive Lung Disease criteria. Of the 202 patients assessed, 43 were subjected to pulmonary function evaluations (spirometry) and FeNO measurements.

resultsOf the 202 elderly patients, 34 had asthma (23 definite and eleven probable), 20 met COPD criteria, 13 presented with an overlap of asthma and COPD, and 135 did not fit the criteria for obstructive pulmonary disease. Among the 43 elderly patients who were subjected to FeNO measurements, ten showed altered results (23.2%) and 33 had normal results (76.7%). The average value of FeNO in patients with definite and probable asthma undergoing this procedure was 29.2 parts per billion whereas that in nonasthmatic patients was 17.5 parts per billion (P=0.0002).

conclusionWe show a clear relationship between FeNO levels and asthma symptoms and previous asthma diagnoses in elderly patients.

Indexed as

AgedAged, 80 and overAsthmaBrazilBreath TestsComorbidityCross-Sectional StudiesExhalationFemaleHumansMaleMiddle AgedNitric OxidePulmonary Disease, Chronic ObstructiveSpirometryNitric Oxideasthmachronic obstructive pulmonary diseaseelderly patientsnitric oxide

Identifiers

PMID27274212
PMCPMC4869629
OpenAlexW2367439372

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.