ArticleProceedings of the National Academy of Sciences of the United States of America2016
Overexpression of a pH-sensitive nitrate transporter in rice increases crop yields.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 158 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
158 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Genetically modified crops are superior in their nitrogen use efficiency-A meta-analysis of three major cereals.Scientific reports · 2020Pooled it
- Breeding for Resilient Cereals: Integrating Molecular Networks and Trait-Based Selection to Improve Nitrogen and Water Use Efficiencies.Plant, cell & environment · 2026Review
- Natural variation in BRN1 enhances nitrogen sensitivity to improve rice nitrogen use efficiency.Nature communications · 2026Article
- Genome-wide analyses of NPF and NRT2 reveal a potential role for a key gene, CqNRT2.2, in the quinoa response to nitrate.BMC plant biology · 2026Article
- The Advantaged Salt Inducible Suaeda salsa SsNRT2.5 and Its Promoter Significantly Enhance Nitrate Transport Efficiency and Salt Tolerance in Transgenic Arabidopsis and Rice.Plant biotechnology journal · 2026Article
- ZmPEPCK2 enhances nutritional quality and yield potential by synchronizing carbon and nitrogen metabolism in maize kernels.Plant communications · 2026Article
- QTL-Seq and pyramiding of yield-related loci from wild rice (Molecular breeding : new strategies in plant improvement · 2026Article
- Root system architecture modulates nitrogen uptake and use efficiency, influencing grain yield in rice.Scientific reports · 2026Article
- Nitrogen Management in Crop-Soil-Environment Systems: Pathways Toward Sustainable and Climate-Resilient Agriculture.International journal of molecular sciences · 2026Review
- A genetic module boosts grain yield and nitrogen use efficiency by improving nitrate transport in maize.Nature genetics · 2026Article
- Physiological and Molecular Mechanisms of Nitrogen Regulation on Grain Quality in Cereal Crops at Later Stages.International journal of molecular sciences · 2026Review
- The transcription factor OsMADS61 positively regulates root elongation and nitrogen use efficiency in rice.Plant communications · 2026Article
- Improving nitrogen use efficiency ofFrontiers in plant science · 2026Article
- Effects of OsNRT2.3b transgenosis on lettuce antioxidant capacity and nitrogen metabolism under low nitrogen.PloS one · 2026Article
- Diversity of root system architecture and root-shoot biomass allocation in industrial hemp (Cannabis sativa L.).PloS one · 2026Article
- High-throughput screening for biostimulant discovery: opportunities to enhance nitrogen use efficiency.Frontiers in plant science · 2026Review
- Exploring the Effects ofPlants (Basel, Switzerland) · 2025Article
- OsNRT1.1B-OsCNGC14/16-CaAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- The fluorescent probe DISBAC2(3) provides a high-throughput screening tool for evaluating abiotic stress tolerance in plants.Plant physiology · 2025Article
- Nitrogen Use Efficiency in Agriculture: Integrating Biotechnology, Microbiology, and Novel Delivery Systems for Sustainable Agriculture.Plants (Basel, Switzerland) · 2025Review
98 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
10 authors.
Funding
Abstract
Cellular pH homeostasis is fundamental for life, and all cells adapt to maintain this balance. In plants, the chemical form of nitrogen supply, nitrate and ammonium, is one of the cellular pH dominators. We report that the rice nitrate transporter OsNRT2.3 is transcribed into two spliced isoforms with a natural variation in expression ratio. One splice form, OsNRT2.3b is located on the plasma membrane, is expressed mainly in the phloem, and has a regulatory motif on the cytosolic side that acts to switch nitrate transport activity on or off by a pH-sensing mechanism. High OsNRT2.3b expression in rice enhances the pH-buffering capacity of the plant, increasing N, Fe, and P uptake. In field trials, increased expression of OsNRT2.3b improved grain yield and nitrogen use efficiency (NUE) by 40%. These results indicate that pH sensing by the rice nitrate transporter OsNRT2.3b is important for plant adaption to varied N supply forms and can provide a target for improving NUE.
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