Evidence map›Paper›PMID 27274049›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2016

Early farmers from across Europe directly descended from Neolithic Aegeans.

Zuzana Hofmanová, Susanne Kreutzer, Garrett Hellenthal, Christian Sell, Yoan Diekmann, David Díez-Del-Molino, Lucy van Dorp, Saioa López, Athanasios Kousathanas, Vivian Link and 29 more

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Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 200 papers.

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0cells of the map it votes in
200citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

200 citing papers in PubMed.

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  6. Fifteen thousand years of bioarchaeological data reveal life history trade-offs among Europe's first farmers.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  11. Global patterns of natural selection inferred using ancient DNA.bioRxiv : the preprint server for biology · 2026
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140 more citing papers are in PubMed but not listed here.

4 · The record

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5 · Who and what money

Authors and funding

39 authors.

Zuzana HofmanováPalaeogenetics Group, Johannes Gutenberg University Mainz, 55099 Mainz, Germany;
Susanne KreutzerPalaeogenetics Group, Johannes Gutenberg University Mainz, 55099 Mainz, Germany;
Garrett HellenthalDepartment of Genetics, Evolution, and Environment, University College London, London WC1E 6BT, United Kingdom;
Christian SellPalaeogenetics Group, Johannes Gutenberg University Mainz, 55099 Mainz, Germany;
Yoan DiekmannDepartment of Genetics, Evolution, and Environment, University College London, London WC1E 6BT, United Kingdom;
David Díez-Del-MolinoDepartment of Genetics, Evolution, and Environment, University College London, London WC1E 6BT, United Kingdom;
Lucy van DorpDepartment of Genetics, Evolution, and Environment, University College London, London WC1E 6BT, United Kingdom;
Saioa LópezDepartment of Genetics, Evolution, and Environment, University College London, London WC1E 6BT, United Kingdom;
Athanasios KousathanasDepartment of Biology, University of Fribourg, 1700 Fribourg, Switzerland; Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland;
Vivian LinkDepartment of Biology, University of Fribourg, 1700 Fribourg, Switzerland; Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland;
Karola KirsanowPalaeogenetics Group, Johannes Gutenberg University Mainz, 55099 Mainz, Germany;
Lara M CassidyMolecular Population Genetics, Smurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland;
Rui MartinianoMolecular Population Genetics, Smurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland;
Melanie StrobelPalaeogenetics Group, Johannes Gutenberg University Mainz, 55099 Mainz, Germany;
Amelie ScheuPalaeogenetics Group, Johannes Gutenberg University Mainz, 55099 Mainz, Germany; Molecular Population Genetics, Smurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland;
Kostas KotsakisFaculty of Philosophy, School of History and Archaeology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece;
Paul HalsteadDepartment of Archaeology, University of Sheffield, Sheffield S1 4ET, United Kingdom;
Sevi TriantaphyllouFaculty of Philosophy, School of History and Archaeology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece;
Nina Kyparissi-ApostolikaHonorary Ephor of Antiquities, Hellenic Ministry of Culture & Sports, 106 82 Athens, Greece;
Dushka Urem-KotsouDepartment of History and Ethnology, Democritus University of Thrace, 69100 Komotini, Greece;ORCID 0000-0002-9534-6340
Christina ZiotaEphorate of Antiquities of Florina, Hellenic Ministry of Culture & Sports, 106 82 Athens, Greece;
Fotini AdaktylouEphorate of Antiquities of Chalkidiki and Mount Athos, Hellenic Ministry of Culture & Sports, 106 82 Athens, Greece;
Shyamalika GopalanDepartment of Ecology and Evolution, Stony Brook University, Stony Brook, New York 11794-5245;
Dean M BoboDepartment of Ecology and Evolution, Stony Brook University, Stony Brook, New York 11794-5245;
Laura WinkelbachPalaeogenetics Group, Johannes Gutenberg University Mainz, 55099 Mainz, Germany;
Jens BlöcherPalaeogenetics Group, Johannes Gutenberg University Mainz, 55099 Mainz, Germany;
Martina UnterländerPalaeogenetics Group, Johannes Gutenberg University Mainz, 55099 Mainz, Germany;
Christoph LeuenbergerDepartment of Mathematics, University of Fribourg, 1700 Fribourg, Switzerland;
Çiler ÇilingiroğluDepartment of Protohistory and Near Eastern Archeology, Faculty of Letters, Ege University, 35100 Bornova, Izmir, Turkey;
Barbara HorejsInstitute of Oriental and European Archaeology, Austrian Academy of Sciences, 1010 Vienna, Austria;
Fokke GerritsenNetherlands Institute in Turkey, Beyoglu 34433, Istanbul, Turkey;
Stephen J ShennanInstitute of Archaeology, University College London, London WC1H 0PY, United Kingdom;
Daniel G BradleyMolecular Population Genetics, Smurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland;
Mathias CurratAnthropology Unit, Department of Genetics & Evolution, University of Geneva, 1211 Geneva, Switzerland;
Krishna R VeeramahDepartment of Ecology and Evolution, Stony Brook University, Stony Brook, New York 11794-5245;
Daniel WegmannDepartment of Biology, University of Fribourg, 1700 Fribourg, Switzerland; Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland;ORCID 0000-0003-2866-6739
Mark G ThomasDepartment of Genetics, Evolution, and Environment, University College London, London WC1E 6BT, United Kingdom;
Christina PapageorgopoulouLaboratory of Anthropology, Department of History and Ethnology, Democritus University of Thrace, 69100 Komotini, Greece cpapage@he.duth.gr jburger@uni-mainz.de.
Joachim BurgerPalaeogenetics Group, Johannes Gutenberg University Mainz, 55099 Mainz, Germany; cpapage@he.duth.gr jburger@uni-mainz.de.

Funding

Austrian Science Fund FWF Y 528Wellcome Trust
6 · The paper itself

Abstract

Farming and sedentism first appeared in southwestern Asia during the early Holocene and later spread to neighboring regions, including Europe, along multiple dispersal routes. Conspicuous uncertainties remain about the relative roles of migration, cultural diffusion, and admixture with local foragers in the early Neolithization of Europe. Here we present paleogenomic data for five Neolithic individuals from northern Greece and northwestern Turkey spanning the time and region of the earliest spread of farming into Europe. We use a novel approach to recalibrate raw reads and call genotypes from ancient DNA and observe striking genetic similarity both among Aegean early farmers and with those from across Europe. Our study demonstrates a direct genetic link between Mediterranean and Central European early farmers and those of Greece and Anatolia, extending the European Neolithic migratory chain all the way back to southwestern Asia.

Indexed as

AgricultureAnthropologyEuropeGenetics, PopulationHumansMediterranean RegionPrincipal Component AnalysisAnatoliaGreeceMesolithicNeolithicpaleogenomics

Identifiers

PMID27274049
PMCPMC4922144

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.