ArticlePhysiological reports2016
Alteration of cardiac autonomic function in patients with newly diagnosed epilepsy.
Article in Physiological reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- If You Care About Autonomic Modulation-Do Not Let Seizure Seizure.Diagnostics (Basel, Switzerland) · 2026Article
- Enhanced subjective performance achievement in wind instrument playing through positive memory recall: effects of sympathetic activation and emotional valence.Frontiers in psychology · 2025Article
- Electrocardiogram Abnormalities and Associated Factors Among People with and without Epilepsy Attending the Outpatient Department at Referral Hospitals in Amhara Regional State, Northern Ethiopia, 2022: Institutional-Based Comparative Cross-Sectional Study.Neuropsychiatric disease and treatment · 2023Article
- Evaluation of Heart Rate Variability Parameters During Awake and Sleep in Refractory and Controlled Epileptic Patients.International journal of general medicine · 2022Article
- Heart Rate Variability in Insulo-Opercular Epilepsy.Brain sciences · 2021Article
- Differences in heart rate variability and body composition in breast cancer survivors and women without cancer.Scientific reports · 2021Article
- Electrocardiographic Abnormalities and Mortality in Epilepsy Patients.Medicina (Kaunas, Lithuania) · 2021Article
- Blood Pressure in Seizures and Epilepsy.Frontiers in neurology · 2019Review
- Alteration of cardiac autonomic function in patients with newly diagnosed epilepsy.Physiological reports · 2016Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the study was to determine if heart rate variability (HRV) showed any changes in patients with newly diagnosed epilepsy in comparison with controls. Sixty-five patients with epilepsy (38 males and 27 females), aged 30-50 years, who had never previously received treatment with antiepileptic drugs were eligible for inclusion in this study. Resting electrocardiogram (ECG) at spontaneous respiration was recorded for 5 min in supine position. Time-domain analysis, frequency-domain analysis, and Poincare plot of HRV were recorded from ECG In time-domain measures, the square root of the mean of the sum of the squares of differences between adjacent RR intervals (RMSSD) and percentage of consecutive RR intervals that differ by more than 50 msec (pNN50) were significantly less in patients with epilepsy. In frequency-domain measures, high frequency [(HF) msec(2)], HF (nu), and low frequency [LF (msec(2))] were significantly less in patients with epilepsy while LF (nu) and LF/HF were significantly high in patients with epilepsy. In Poincare plot, standard deviation perpendicular to line of Poincare plot (SD1) and standard deviation along the line of entity in Poincare plot (SD2) were significantly less in patients with epilepsy. Our results suggest that epileptic patients have an impact on the cardiac autonomic function as measured by HRV.
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