Evidence map›Paper›PMID 27273843›Full record

ArticleAddiction (Abingdon, England)2017

'PrEP is not ready for our community, and our community is not ready for PrEP': pre-exposure prophylaxis for HIV for people who inject drugs and limits to the HIV prevention response.

Andy Guise, Eliot Ross Albers, Steffanie A Strathdee

Abstract read
In one paragraph

Article in Addiction (Abingdon, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Trial
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  8. Toward a Philosophy of Harm Reduction.Health care analysis : HCA : journal of health philosophy and policy · 2020
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Andy GuiseDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Eliot Ross AlbersInternational Network of People who Use Drugs, London, UK.
Steffanie A StrathdeeDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.

Funding

Impact of Drug Policy Reform on the HIV Risk Environment among IDUs in TijuanaR37DA019829 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI STRATHDEE, STEFFANIE A. · 2010 to 2019
$6.7M
NIDA NIH HHS R37 DA019829
6 · The paper itself

Abstract

BACKGROUND AND

aimsPre-exposure prophylaxis for HIV, or 'PrEP', is the use of antiretroviral medicines by people who are HIV-negative to protect themselves against acquiring HIV. PrEP has shown efficacy for preventing HIV acquisition. Despite the potential, many concerns have been voiced by people who inject drugs (PWID) and their organizations. There is a need to engage with these views and ensure their integration in to policy and strategy. This paper presents PWID views on PrEP to foster the uptake of these opinions into scientific and policy debate around PrEP

methodsCritical analysis of a report of a community consultation led by the International Network of People who Use Drugs (INPUD).

resultsThe INPUD report highlights enthusiasm from PWID for PrEP, but also three main concerns: the feasibility and ethics of PrEP, its potential use as a substitute for other harm reduction strategies and how a focus on PrEP heralds a re-medicalization of HIV. Each concern relates to evidenced gaps in essential services or opposition to harm reduction and PWID human rights.

conclusionsPeople who use drugs have fundamental concerns about the potential impacts of pre-exposure prophylaxis for HIV which reflect a 'fault line' in HIV prevention: a predominance of biomedical approaches over community perspectives. Greater community engagement in HIV prevention strategy is needed, or we risk continuing to ignore the need for action on the underlying structural drivers and social context of the HIV epidemic.

Indexed as

Harm ReductionSubstance Abuse, IntravenousAnti-HIV AgentsCommunity ParticipationEthics, MedicalFeasibility StudiesHIV InfectionsHumansPre-Exposure ProphylaxisAnti-HIV AgentsBiomedicalcommunityHIVinjection drug usePrEPprevention

Identifiers

PMID27273843
PMCPMC5145792

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.