Evidence map›Paper›PMID 27273767›Full record

ArticleNature neuroscience2016

Topographical representation of odor hedonics in the olfactory bulb.

Florence Kermen, Maëllie Midroit, Nicola Kuczewski, Jérémy Forest, Marc Thévenet, Joëlle Sacquet, Claire Benetollo, Marion Richard, Anne Didier, Nathalie Mandairon

Abstract read
PubMed Publisher
In one paragraph

Article in Nature neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Olfactory receptors and human diseases.Cell and tissue research · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Anosmia in COVID-19: Underlying Mechanisms and Assessment of an Olfactory Route to Brain Infection.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2021
    Review
  12. The human olfactory bulb processes odor valence representation and cues motor avoidance behavior.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  13. Review
  14. Article
  15. Review
  16. Noradrenergic Activity in the Olfactory Bulb Is a Key Element for the Stability of Olfactory Memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Florence KermenINSERM, U1028, CNRS, UMR5292, Lyon Neuroscience Research Centre, Neuroplasticity and Neuropathology of Olfactory Perception Team, University Lyon 1, University of Lyon, Lyon, France.
Maëllie MidroitINSERM, U1028, CNRS, UMR5292, Lyon Neuroscience Research Centre, Neuroplasticity and Neuropathology of Olfactory Perception Team, University Lyon 1, University of Lyon, Lyon, France.
Nicola KuczewskiINSERM, U1028, CNRS, UMR5292, Lyon Neuroscience Research Centre, Neuroplasticity and Neuropathology of Olfactory Perception Team, University Lyon 1, University of Lyon, Lyon, France.
Jérémy ForestINSERM, U1028, CNRS, UMR5292, Lyon Neuroscience Research Centre, Neuroplasticity and Neuropathology of Olfactory Perception Team, University Lyon 1, University of Lyon, Lyon, France.
Marc ThévenetINSERM, U1028, CNRS, UMR5292, Lyon Neuroscience Research Centre, Neuroplasticity and Neuropathology of Olfactory Perception Team, University Lyon 1, University of Lyon, Lyon, France.
Joëlle SacquetINSERM, U1028, CNRS, UMR5292, Lyon Neuroscience Research Centre, Neuroplasticity and Neuropathology of Olfactory Perception Team, University Lyon 1, University of Lyon, Lyon, France.
Claire BenetolloINSERM, U1028, CNRS, UMR5292, Lyon Neuroscience Research Center, Neurogenetic and Optogenetic Platform, University Lyon 1, University of Lyon, Lyon, France.
Marion RichardINSERM, U1028, CNRS, UMR5292, Lyon Neuroscience Research Centre, Neuroplasticity and Neuropathology of Olfactory Perception Team, University Lyon 1, University of Lyon, Lyon, France.
Anne DidierINSERM, U1028, CNRS, UMR5292, Lyon Neuroscience Research Centre, Neuroplasticity and Neuropathology of Olfactory Perception Team, University Lyon 1, University of Lyon, Lyon, France.
Nathalie MandaironINSERM, U1028, CNRS, UMR5292, Lyon Neuroscience Research Centre, Neuroplasticity and Neuropathology of Olfactory Perception Team, University Lyon 1, University of Lyon, Lyon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hedonic value is a dominant aspect of olfactory perception. Using optogenetic manipulation in freely behaving mice paired with immediate early gene mapping, we demonstrate that hedonic information is represented along the antero-posterior axis of the ventral olfactory bulb. Using this representation, we show that the degree of attractiveness of odors can be bidirectionally modulated by local manipulation of the olfactory bulb's neural networks in freely behaving mice.

Indexed as

AnimalsBehavior, AnimalMaleMice, Inbred C57BLNerve NetOdorantsOlfactory BulbOlfactory PerceptionSmell

Identifiers

PMID27273767

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.