Evidence map›Paper›PMID 27273643›Full record

ArticleThe American journal of tropical medicine and hygiene2017

Loop-Mediated Isothermal Amplification for Detection of the 5.8S Ribosomal Ribonucleic Acid Internal Transcribed Spacer 2 Gene Found in

Olga V Nikolskaia, Oriel M M Thekisoe, J Stephen Dumler, Dennis J Grab

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. NTD Diagnostics for Disease Elimination: A Review.Diagnostics (Basel, Switzerland) · 2020
    Review
  6. Loop-Mediated Isothermal Amplification Test forJournal of tropical medicine · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Olga V NikolskaiaDepartment of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland.
Oriel M M ThekisoeUnit for Environmental Sciences and Management, North-West University, Potchefstroom, South Africa.
J Stephen DumlerDepartment of Pathology, University of Maryland School of Medicine, Baltimore, Maryland.
Dennis J GrabDepartment of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland. dgrab1@jhmi.edu.
Johns Hopkins Medicine · USNorth-West University · ZAUniversity of Maryland, College Park · US

Funding

Diagnosis of gambiense HATR01AI082695 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GRAB, DENNIS JOHN · 2009 to 2012
$1.4M
Using protein-DNA chimeras for HAT diagnosisR21AI079282 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GRAB, DENNIS JOHN · 2009 to 2010
$436k
NIAID NIH HHS R01 AI082695NIAID NIH HHS R21 AI079282
6 · The paper itself

Abstract

The loop-mediated isothermal amplification (LAMP) assay with its advantages of cost effectiveness, rapidity, and simplicity, has evolved as a sensitive and specific method for the detection of African trypanosomes. Highly sensitive LAMP reactions specific for

Indexed as

Early DiagnosisGenes, ProtozoanHumansNucleic Acid Amplification TechniquesRNA, Ribosomal, 5.8STrypanosoma brucei gambienseTrypanosomiasis, AfricanRNA, Ribosomal, 5.8S

Identifiers

PMID27273643
PMCPMC5303023
OpenAlexW2415259116

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.