ReviewNature reviews. Gastroenterology & hepatology2016
Critical comparison of elastography methods to assess chronic liver disease.
Review in Nature reviews. Gastroenterology & hepatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
105 citing papers in PubMed, 1 synthesis or guideline pooled it, 241 citations in OpenAlex.
- Assessment of biopsy-proven liver fibrosis by two-dimensional shear wave elastography: An individual patient data-based meta-analysis.Hepatology (Baltimore, Md.) · 2018Pooled it
- Trial
- Observations of blue-stripe artefacts in 2D SWE not reported in guidelines and their influence on diagnostic accuracy-A technical note.Radiology case reports · 2026Article
- When new therapies arrive, we should think more: The unseen challenges of immunotherapy-induced remodeling.World journal of clinical cases · 2025Article
- [Current research progress status in identifying hepatocellular ballooning degeneration in nonalcoholic steatohepatitis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025Review
- A U-shaped relationship between body mass index and the risk of elevated liver stiffness in older people: evidence from the 5-year retrospective cohort study.International journal of obesity (2005) · 2025Article
- Possible link between steatotic liver diseases, severe COVID-19 and cognitive impairment in post-COVID-19 syndrome.Infection · 2025Article
- Prevention of Antipsychotic-Induced Weight Gain: Beyond Metformin.Schizophrenia bulletin · 2025Article
- Usefulness of Endoscopic Ultrasound Strain Elastography for Measuring Liver Stiffness and the Role of Blood Cytokeratin 18 Levels as a Surrogate Marker of Fibrosis.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2025Article
- Low-risk individuals with primary biliary cholangitis and significant liver stiffness: prognosis and treatment.Hepatology international · 2025Article
- Network pharmacology-guided investigation of Fuzheng Yanggan Huaxian decoction in a CCLAmerican journal of translational research · 2025Article
- Association between weekend warriors and MASLD-a cross-sectional study of the NHANES database 2017-2020.Frontiers in medicine · 2025Article
- Two-Dimensional and Point Shear-Wave Elastography to Predict Esophageal Varices and Clinically Significant Portal Hypertension in Patients with Chronic Liver Disease.Journal of clinical medicine · 2024Article
- Non-Invasive versus Invasive Assessment of Portal Hypertension in Chronic Liver Disease.GE Portuguese journal of gastroenterology · 2024Review
- Explainable machine learning model for predicting the risk of significant liver fibrosis in patients with diabetic retinopathy.BMC medical informatics and decision making · 2024Article
- Ultrasound Shear Wave Elastography Evaluation of the Liver and Implications for Perioperative Medicine.Journal of clinical medicine · 2024Review
- Elevated non-HDL-C to HDL-C ratio as a marker for NAFLD and liver fibrosis risk: a cross-sectional analysis.Frontiers in endocrinology · 2024Article
- Elevated ALT/AST ratio as a marker for NAFLD risk and severity: insights from a cross-sectional analysis in the United States.Frontiers in endocrinology · 2024Article
- Nonalcoholic Fatty Liver Disease and Staging of Hepatic Fibrosis.Advances in experimental medicine and biology · 2024Review
- A J-shaped relationship between body mass index and the risk of elevated liver stiffness: a cross-sectional study.European journal of medical research · 2023Article
45 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Staging of liver fibrosis and diagnosis, or exclusion, of early compensated liver cirrhosis are important in the treatment decisions and surveillance of patients with chronic liver disease. Good diagnostic accuracy, increased availability and the possibility to perform follow-up examinations led to the implementation of noninvasive methods into clinical practice. Noninvasive tests are increasingly included in national and international guidelines, leaving liver biopsy reserved for patients with unexplained discordance or suspected additional aetiologies of liver disease. In addition to staging of liver fibrosis, data on the prognostic value of these methods have increased in the past few years and are of great importance for patient care. This Review focuses on elastography methods for noninvasive assessment of liver fibrosis, disease severity and prognosis. Although liver elastography started with transient elastography, at present all large ultrasonography companies offer an elastography technique integrated in their machines. The goal of this Review is to summarize the methodological problems of noninvasive tests in general, in addition to providing an overview on currently available techniques and latest developments in liver elastography.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.