Evidence map›Paper›PMID 27273018›Full record

ReviewInternal and emergency medicine2016

Emerging hepatic syndromes: pathophysiology, diagnosis and treatment.

Gaetano Bertino, Graziella Privitera, Francesco Purrello, Shirin Demma, Emanuele Crisafulli, Luisa Spadaro, Nikolaos Koukias, Emmanuel A Tsochatzis

Abstract readReview
PubMed Publisher
In one paragraph

Review in Internal and emergency medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

  1. Liver Kidney Crosstalk: Hepatorenal Syndrome.World journal of hepatology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Gaetano BertinoHepatology Unit, Department of Clinical and Experimental Medicine, University of Catania, Policlinico "G. Rodolico", Catania, Italy.
Graziella PriviteraInternal Medicine, Department of Clinical and Experimental Medicine, University of Catania, Ospedale Garibaldi-Nesima, Catania, Italy.
Francesco PurrelloInternal Medicine, Department of Clinical and Experimental Medicine, University of Catania, Ospedale Garibaldi-Nesima, Catania, Italy.
Shirin DemmaHepatology Unit, Department of Clinical and Experimental Medicine, University of Catania, Policlinico "G. Rodolico", Catania, Italy.
Emanuele CrisafulliHepatology Unit, Department of Clinical and Experimental Medicine, University of Catania, Policlinico "G. Rodolico", Catania, Italy.
Luisa SpadaroInternal Medicine, Department of Clinical and Experimental Medicine, University of Catania, Ospedale Garibaldi-Nesima, Catania, Italy.
Nikolaos KoukiasUCL Institute for Liver and Digestive Health and Sheila Sherlock Liver Unit, Royal Free Hospital and UCL, London, UK.
Emmanuel A TsochatzisUCL Institute for Liver and Digestive Health and Sheila Sherlock Liver Unit, Royal Free Hospital and UCL, London, UK. e.tsochatzis@ucl.ac.uk.
University of Catania · ITThe Royal Free Hospital · GBOspedale Garibaldi · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver cirrhosis is a major cause of morbidity and mortality worldwide, mainly due to complications of portal hypertension. In this article, we review the current understanding on the pathophysiology, the diagnostic criteria and the available therapeutic options for patients with emerging hepatic syndromes in cirrhosis, namely the hepatorenal, hepato-adrenal and hepatopulmonary syndrome. The hepatorenal syndrome is a well-recognized complication of advanced cirrhosis and is usually associated with an accelerated course to death unless liver transplantation is performed. The hepatopulmonary syndrome is often missed in the evaluation of patients with cirrhosis; however, early recognition is essential for the efficient management of individual patients. The hepato-adrenal syndrome, although not fully characterized, offers an exciting field for research and potential therapeutic interventions.

Indexed as

Acute Kidney InjuryAdrenal InsufficiencyAscitesCreatinineEvidence-Based MedicineHepatorenal SyndromeHumansHypertension, PortalLiver CirrhosisLiver TransplantationLypressinMidodrineNorepinephrineOctreotidePlasma SubstitutesPortasystemic Shunt, Transjugular IntrahepaticCreatinineLypressinMidodrineNorepinephrineOctreotidePlasma SubstitutesSerum AlbuminTerlipressinVasodilator AgentsVasopressinsCirrhosisHepato-adrenalHepatopulmonaryHepatorenal

Identifiers

PMID27273018
OpenAlexW2409366293

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.