Observational studyPediatric cardiology2016
Predictors of Early Extubation After Pediatric Cardiac Surgery: A Single-Center Prospective Observational Study.
Observational study in Pediatric cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Different extubation protocols for adult cardiac surgery: a systematic review and pairwise and network meta-analysis.BMC anesthesiology · 2025Pooled it
- The association of vasoactive-inotropic score and surgical patients' outcomes: a systematic review and meta-analysis.Systematic reviews · 2024Pooled it
- Vaso-active inotropic scores: Clinical value, pros and cons.JHLT open · 2026Article
- Ultra-fast-track anesthesia in cardiac surgery: perioperative outcomes, patient selection, and implementation strategies-a narrative review.Frontiers in cardiovascular medicine · 2026Review
- Early extubation after pediatric cardiac surgery.Anesthesia and pain medicine · 2024Article
- Review
- Predictors and outcomes of extubation failures in a pediatric intensive care unit: A retrospective study.Journal of Taibah University Medical Sciences · 2024Article
- Comparison of Three Different Multiple Organ Dysfunction Scores for Predicting Mortality after Neonatal Cardiac Surgery.Children (Basel, Switzerland) · 2023Article
- Assessment of the factors that affect fast-track or early extubation following pediatric cardiac surgery.Turk gogus kalp damar cerrahisi dergisi · 2023Article
- Is Early Extubation Associated with Better Outcomes After Neonatal Congenital Heart Disease Surgery?Journal of pediatric intensive care · 2022Article
- Prognostic value of biomarkers after cardiopulmonary bypass in pediatrics: The prospective PANCAP study.PloS one · 2019Observational
- Predictors and outcome of early extubation in infants postcardiac surgery: A single-center observational study.Annals of cardiac anaesthesiaObservational
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This prospective, observational, single-center study aimed to determine the perioperative predictors of early extubation (<24 h after cardiac surgery) in a cohort of children undergoing cardiac surgery. Children aged between 1 month and 18 years who were consecutively admitted to pediatric intensive care unit after cardiac surgery for congenital heart disease between January 2012 and June 2014. Ninety-nine patients were qualified for inclusion during the study period. The median duration of mechanical ventilation was 20 h (range 1-480), and 64 patients were extubated within 24 h. Four of them failed the initial attempt at extubation, and the success rate of early extubation was 60.6 %. Older patient age (p = .009), greater body weight (p = .009), absence of preoperative pulmonary hypertension (p = .044), lower RACHS-1 category (OR, 3.8; 95 % CI 1.35-10.7; p < .05), shorter cardiopulmonary bypass (p = .008) and cross-clamp (p = .022) times, lower PRISM III-24 (p < .05) and PELOD (p < .05) scores, lower inotropic score (p < .05) and vasoactive-inotropic score (p < .05), and lower number of organ failures (OR, 2.26; 95 % CI 1.30-3.92; p < .05) were associated with early extubation. Our study establishes that early extubation can be accomplished within the first 24 h after surgery in low- to medium-risk pediatric cardiac surgery patients, especially in older ones undergoing low-complexity procedures. A large prospective multiple institution trial is necessary to identify the predictors and benefits of early extubation and to facilitate defined guidelines for early extubation.
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