ArticleMarine drugs2016
Coral Carbonic Anhydrases: Regulation by Ocean Acidification.
Article in Marine drugs, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 47 citations in OpenAlex.
- Changes in host gene expression patterns underpin responses of the coral Stylophora pistillata to nutrient stress.Scientific reports · 2025Article
- Extreme Environmental Variability Induces Frontloading of Coral Biomineralisation Genes to Maintain Calcification Under pCOMolecular ecology · 2025Article
- Progress of Section "Biochemistry" in 2022.International journal of molecular sciences · 2023Article
- Mechanisms and potential immune tradeoffs of accelerated coral growth induced by microfragmentation.PeerJ · 2022Article
- Combined responses of primary coral polyps and their algal endosymbionts to decreasing seawater pH.Proceedings. Biological sciences · 2021Article
- Intracellular pH regulation: characterization and functional investigation of HBMC molecular and cell biology · 2021Article
- The spatial network of skeletal proteins in a stony coral.Journal of the Royal Society, Interface · 2021Article
- Evolution of Protein-Mediated Biomineralization in Scleractinian Corals.Frontiers in genetics · 2021Article
- Activation studies of the β-carbonic anhydrases fromJournal of enzyme inhibition and medicinal chemistry · 2020Article
- First sequencing of ancient coral skeletal proteins.Scientific reports · 2020Article
- Ocean acidification promotes broad transcriptomic responses in marine metazoans: a literature survey.Frontiers in zoology · 2020Review
- Article
- How corals made rocks through the ages.Global change biology · 2020Review
- Carbonic Anhydrase as a Biomarker of Global and Local Impacts: Insights from Calcifying Animals.International journal of molecular sciences · 2019Review
- Rare genetic variation and balanced polymorphisms are important for survival in global change conditions.Proceedings. Biological sciences · 2019Article
- Comparison of the Anion Inhibition Profiles of the α-CA Isoforms (SpiCA1, SpiCA2 and SpiCA3) from the Scleractinian Coral Stylophora pistillata.International journal of molecular sciences · 2018Article
- Biochemical characterization of the native α-carbonic anhydrase purified from the mantle of the Mediterranean mussel, Mytilus galloprovincialis.Journal of enzyme inhibition and medicinal chemistry · 2017Article
- Transcriptomic response of the Antarctic pteropod Limacina helicina antarctica to ocean acidification.BMC genomics · 2017Article
- Sequence Analysis, Kinetic Constants, and Anion Inhibition Profile of the Nacrein-Like Protein (CgiNAP2X1) from the Pacific Oyster Magallana gigas (Ex-Crassostrea gigas).Marine drugs · 2017Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Global change is a major threat to the oceans, as it implies temperature increase and acidification. Ocean acidification (OA) involving decreasing pH and changes in seawater carbonate chemistry challenges the capacity of corals to form their skeletons. Despite the large number of studies that have investigated how rates of calcification respond to ocean acidification scenarios, comparatively few studies tackle how ocean acidification impacts the physiological mechanisms that drive calcification itself. The aim of our paper was to determine how the carbonic anhydrases, which play a major role in calcification, are potentially regulated by ocean acidification. For this we measured the effect of pH on enzyme activity of two carbonic anhydrase isoforms that have been previously characterized in the scleractinian coral Stylophora pistillata. In addition we looked at gene expression of these enzymes in vivo. For both isoforms, our results show (1) a change in gene expression under OA (2) an effect of OA and temperature on carbonic anhydrase activity. We suggest that temperature increase could counterbalance the effect of OA on enzyme activity. Finally we point out that caution must, thus, be taken when interpreting transcriptomic data on carbonic anhydrases in ocean acidification and temperature stress experiments, as the effect of these stressors on the physiological function of CA will depend both on gene expression and enzyme activity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.