Evidence map›Paper›PMID 27271033›Full record

ArticlePediatric nephrology (Berlin, Germany)2016

Prolonged respiratory disorder predicts adverse prognosis in infants with end-stage kidney disease.

Tomoyuki Sakai, Yoshitaka Murakami, Yusuke Okuda, Riku Hamada, Yuko Hamasaki, Kenji Ishikura, Hiroshi Hataya, Masataka Honda

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Tomoyuki SakaiDepartment of Pediatrics, Shiga University of Medical Science, Tsukinowa, Seta, Otsu, Shiga, 520-2192, Japan. sakai-tomoyuki@umin.ac.jp.
Yoshitaka MurakamiDepartment of Medical Statistics, Toho University Faculty of Medicine, Tokyo, Japan.
Yusuke OkudaDepartment of Pediatrics, Shiga University of Medical Science, Tsukinowa, Seta, Otsu, Shiga, 520-2192, Japan.
Riku HamadaDepartment of Nephrology, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.
Yuko HamasakiDepartment of Pediatric Nephrology, Toho University Faculty of Medicine, Tokyo, Japan.
Kenji IshikuraDivision of Nephrology and Rheumatology, National Center for Child Health and Development, Tokyo, Japan.
Hiroshi HatayaDepartment of Nephrology, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.
Masataka HondaDepartment of Nephrology, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.
Tokyo Metropolitan Children's Medical Center · JPShiga University of Medical Science · JPToho University · JPNational Center For Child Health and Development · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAmong comorbidities, pulmonary hypoplasia (PH) is known as a significant risk factor for mortality in infants with end-stage kidney disease (ESKD). However, the final outcomes of infants with both ESKD and PH are still not well defined, as the diagnosis modality, and definition of PH severity remain ambiguous.

methodsChildren initiating peritoneal dialysis during infancy from 1990 to 2015 were followed until death, date of last contact, or the end of 2015. We examined the long-term outcome of children with congenital pulmonary disorders by studying infants with prolonged respiratory disorders of greater than 28 days duration after birth and evaluated risk factors for mortality.

resultsForty-six children were followed (median follow-up, 9.23 years), and classified as children without (n = 38; Group A) or with (n = 8; Group B) a prolonged respiratory disorder. Overall actuarial 5 year survival rate in this cohort was 79.5 %. The survival curve in Group B showed a significant decline compared with Group A. Prolonged respiratory disorder was significantly associated with mortality by multivariate analysis (hazard ratio, 8.32).

conclusionsInfants who initiate peritoneal dialysis complicated by prolonged respiratory disorders have increased adverse risk factors for mortality; therefore, withholding aggressive treatment should be considered.

Indexed as

Abnormalities, MultipleComorbidityFemaleFollow-Up StudiesHumansInfantKaplan-Meier EstimateKidney Failure, ChronicLungLung DiseasesPeritoneal DialysisPrognosisProportional Hazards ModelsRetrospective StudiesRisk FactorsSurvival RateEnd-stage kidney diseaseInfantPeritoneal dialysisPulmonary hypoplasiaSurvival analysisWithholding treatment

Identifiers

PMID27271033
OpenAlexW2419648956

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.