Evidence map›Paper›PMID 27270989›Full record

ReviewJournal of neurogastroenterology and motility2016

Diagnosis and Treatment of Dyssynergic Defecation.

Satish S C Rao, Tanisa Patcharatrakul

2 registry-linked trialsOpen access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of neurogastroenterology and motility, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 116 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
116citing papers in PubMed, 4 pooled it
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07482696 narecruitingnot on this mapstarted 2026, after this paper: background citation

Effects of Game-Based Electromyographic Biofeedback Therapy on Quality of Life and Sleep Quality in Patients With Dyssynergic Defecation

TypeinterventionalSponsorKocaeli UniversityRan2026 to 2026Enrolled36ConditionsDefecation DisorderArmsGame-Based Electromyographic (EMG) Biofeedback Therapy, Sham Control
NCT07705542 narecruitingnot on this mapstarted 2026, after this paper: background citation

Analysing the Impact of Balloon Inflated vs Balloon Deflated Push Manoeuvres in Chronically Constipated Patients During Biofeedback Therapy

TypeinterventionalSponsorHull University Teaching Hospitals NHS TrustRan2026 to 2026Enrolled10ConditionsConstipation, Chronic Constipation, Dyssynergia, AnismusArmsInflating anorectal catheter balloon to defecatory desired volume during push manoeuvres in biofeedback therapy., No intervention
3 · Its place in the literature

Who cites it

116 citing papers in PubMed, 4 syntheses or guidelines pooled it, 250 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
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  9. Review
  10. High-resolution anorectal manometry in chronic constipation-Defining dysfunction beyond diagnosis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Article
  11. High-resolution anorectal manometry profile in patients with chronic constipation versus control.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Article
  12. Review
  13. Article
  14. Short and long-term outcomes of anorectal biofeedback therapy in patients with functional defecation disorders: Efficacy and predictors of response.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Observational
  20. Efficacy of home biofeedback in dyssynergic defaecation: A prospective pilot study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026
    Article

56 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Satish S C RaoDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Augusta University, Augusta, Georgia, USA.
Tanisa PatcharatrakulDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Augusta University, Augusta, Georgia, USA.
Augusta University · USThai Red Cross Society · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dyssynergic defecation is common and affects up to one half of patients with chronic constipation. This acquired behavioral problem is due to the inability to coordinate the abdominal and pelvic floor muscles to evacuate stools. A detailed history, prospective stool diaries, and a careful digital rectal examination will not only identify the nature of bowel dysfunction, but also raise the index of suspicion for this evacuation disorder. Anorectal physiology tests and balloon expulsion test are essential for a diagnosis. Newer techniques such as high-resolution manometry and magnetic resonance defecography can provide mechanistic insights. Recently, randomized controlled trials have shown that biofeedback therapy is more effective than laxatives and other modalities, both in the short term and long term, without side effects. Also, symptom improvements correlated with changes in underlying pathophysiology. Biofeedback therapy has been recommended as the first-line of treatment for dyssynergic defecation. Here, we provide an overview of the burden of illness and pathophysiology of dyssynergic defecation, and how to diagnose and treat this condition with biofeedback therapy.

Indexed as

ConstipationDefecationLaxatives

Identifiers

PMID27270989
PMCPMC4930297
OpenAlexW2413733913

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.