Evidence map›Paper›PMID 27270757›Full record

ArticleScientific reports2016

Reassortment compatibility between PB1, PB2, and HA genes of the two influenza B virus lineages in mammalian cells.

Jin Il Kim, Ilseob Lee, Sehee Park, Joon-Yong Bae, Kirim Yoo, Philippe Lemey, Mee Sook Park, Jin-Won Song, Sun-Ho Kee, Ki-Joon Song and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Pregnancy and pandemics: Interaction of viral surface proteins and placenta cells.Biochimica et biophysica acta. Molecular basis of disease · 2021
    Review
  5. Article
  6. Divergent evolutionary trajectories of influenza B viruses underlie their contemporaneous epidemic activity.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Jin Il KimDepartment of Microbiology, the Institute of Viral Diseases, College of Medicine, Korea University, Seoul 02841, Republic of Korea.
Ilseob LeeDepartment of Microbiology, the Institute of Viral Diseases, College of Medicine, Korea University, Seoul 02841, Republic of Korea.
Sehee ParkDepartment of Microbiology, the Institute of Viral Diseases, College of Medicine, Korea University, Seoul 02841, Republic of Korea.
Joon-Yong BaeDepartment of Microbiology, the Institute of Viral Diseases, College of Medicine, Korea University, Seoul 02841, Republic of Korea.
Kirim YooDepartment of Microbiology, the Institute of Viral Diseases, College of Medicine, Korea University, Seoul 02841, Republic of Korea.
Philippe LemeyDepartment of Microbiology and Immunology, Rega Institute, KU Leuven - University of Leuven, Leuven 3000, Belgium.
Mee Sook ParkDepartment of Microbiology, the Institute of Viral Diseases, College of Medicine, Korea University, Seoul 02841, Republic of Korea.
Jin-Won SongDepartment of Microbiology, the Institute of Viral Diseases, College of Medicine, Korea University, Seoul 02841, Republic of Korea.
Sun-Ho KeeDepartment of Microbiology, the Institute of Viral Diseases, College of Medicine, Korea University, Seoul 02841, Republic of Korea.
Ki-Joon SongDepartment of Microbiology, the Institute of Viral Diseases, College of Medicine, Korea University, Seoul 02841, Republic of Korea.
Man-Seong ParkDepartment of Microbiology, the Institute of Viral Diseases, College of Medicine, Korea University, Seoul 02841, Republic of Korea.
Korea University · KRKU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In addition to influenza A subtypes, two distinct lineages of influenza B virus also cause seasonal epidemics to humans. Recently, Dudas et al. have done evolutionary analyses of reassortment patterns of the virus and suggested genetic lineage relationship between PB1, PB2, and HA genes. Using genetic plasmids and reassortant viruses, we here demonstrate that a homologous lineage PB1-PB2 pair exhibits better compatibility than a heterologous one and that the lineage relationship between PB1 and HA is more important for viral replication than that between PB2 and HA. However, co-adaptation of PB1-PB2-HA genes appears to be affected by complete gene constellation.

Indexed as

AnimalsGenes, ViralInfluenza B virusPhylogenyReassortant VirusesVirus Replication

Identifiers

PMID27270757
PMCPMC4897687
OpenAlexW2409794925

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.