ArticleDatabase : the journal of biological databases and curation2016
Gene regulation knowledge commons: community action takes care of DNA binding transcription factors.
Article in Database : the journal of biological databases and curation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- TFCheckpoint database update, a cross-referencing system for transcription factors from human, mouse and rat.Nucleic acids research · 2024Article
- The Minimum Information about a Molecular Interaction CAusal STatement (MI2CAST).Bioinformatics (Oxford, England) · 2021Article
- Fair trade in building digital knowledge repositories: the knowledge economy as if researchers mattered.Medicine, health care, and philosophy · 2020Article
- Benchmark and integration of resources for the estimation of human transcription factor activities.Genome research · 2019Article
- Harvesting the promise of AOPs: An assessment and recommendations.The Science of the total environment · 2018Review
- MGH: a genome hub for the medicinal plant maca (Lepidium meyenii).Database : the journal of biological databases and curation · 2018Article
- In silico design of context-responsive mammalian promoters with user-defined functionality.Nucleic acids research · 2017Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
A large gap remains between the amount of knowledge in scientific literature and the fraction that gets curated into standardized databases, despite many curation initiatives. Yet the availability of comprehensive knowledge in databases is crucial for exploiting existing background knowledge, both for designing follow-up experiments and for interpreting new experimental data. Structured resources also underpin the computational integration and modeling of regulatory pathways, which further aids our understanding of regulatory dynamics. We argue how cooperation between the scientific community and professional curators can increase the capacity of capturing precise knowledge from literature. We demonstrate this with a project in which we mobilize biological domain experts who curate large amounts of DNA binding transcription factors, and show that they, although new to the field of curation, can make valuable contributions by harvesting reported knowledge from scientific papers. Such community curation can enhance the scientific epistemic process.Database URL: http://www.tfcheckpoint.org.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.