ArticleScientific reports2016
Genetic variations associated with six-white-point coat pigmentation in Diannan small-ear pigs.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Whole-genome sequencing reveals complex structural variations at a major locus linked to pigmented spot sizes in Tianfu goats.BMC genomics · 2025Article
- Omics in mini-livestock: a genomic perspective on the future of sustainable food systems.Frontiers in genetics · 2025Review
- Comparative analysis of the physical and phenotypic traits of native cattle (Veterinary world · 2025Article
- The 1000 Chinese Indigenous Pig Genomes Project provides insights into the genomic architecture of pigs.Nature communications · 2024Article
- Article
- Association between MC1R gene and coat color segregation in Shanxia long black pig and Lulai black pig.BMC genomic data · 2023Article
- Two High-QualityInternational journal of molecular sciences · 2023Article
- Comparison of differentially expressed genes in longissimus dorsi muscle of Diannan small ears, Wujin and landrace pigs using RNA-seq.Frontiers in veterinary science · 2023Article
- Genetic diversity and population structure of six autochthonous pig breeds from Croatia, Serbia, and Slovenia.Genetics, selection, evolution : GSE · 2022Article
- First study on phenotypic and morphological characteristics of Malaysian Kedah-Kelantan cattle (Veterinary world · 2022Article
- Identifying Candidate Genes for Short Gestation Length Trait in Chinese Qingping Pigs by Whole-Genome Resequencing and RNA Sequencing.Frontiers in genetics · 2022Article
- Article
- Whole genome resequencing reveals an association of ABCC4 variants with preaxial polydactyly in pigs.BMC genomics · 2020Article
- Genetic Diversity and Selection Signatures Within Diannan Small-Ear Pigs Revealed by Next-Generation Sequencing.Frontiers in genetics · 2020Article
- Population Genomics Analysis Revealed Origin and High-altitude Adaptation of Tibetan Pigs.Scientific reports · 2019Article
- Comparative Transcriptome Analysis of Mink (Neovison vison) Skin Reveals the Key Genes Involved in the Melanogenesis of Black and White Coat Colour.Scientific reports · 2017Article
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9 authors.
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Abstract
A common phenotypic difference among domestic animals is variation in coat color. Six-white-point is a pigmentation pattern observed in varying pig breeds, which seems to have evolved through several different mechanistic pathways. Herein, we re-sequenced whole genomes of 31 Diannan small-ear pigs from China and found that the six-white-point coat color in Diannan small-ear pigs is likely regulated by polygenic loci, rather than by the MC1R locus. Strong associations were observed at three loci (EDNRB, CNTLN, and PINK1), which explain about 20 percent of the total coat color variance in the Diannan small-ear pigs. We found a mutation that is highly differentiated between six-white-point and black Diannan small-ear pigs, which is located in a conserved noncoding sequence upstream of the EDNRB gene and is a putative binding site of the CEBPB protein. This study advances our understanding of coat color evolution in Diannan small-ear pigs and expands our traditional knowledge of coat color being a monogenic trait.
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