ReviewAsian journal of andrology
Genetic factors contributing to human primary ciliary dyskinesia and male infertility.
Review in Asian journal of andrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 26 citations in OpenAlex.
- Is Male Infertility an Early Warning of More Serious Diseases?Endocrinology · 2026Review
- Exome sequencing-based identification ofFrontiers in molecular biosciences · 2026Article
- Genetic Implications of Male-Reproductive-Health-Associated Comorbidities.Turkish journal of urology · 2022Article
- Distinct Roles of NANOS1 and NANOS3 in the Cell Cycle and NANOS3-PUM1-FOXM1 Axis to Control G2/M Phase in a Human Primordial Germ Cell Model.International journal of molecular sciences · 2022Article
- Article
- Analysis of the sperm flagellar axoneme using gene-modified mice.Experimental animals · 2020Review
- Biallelic mutations of CFAP74 may cause human primary ciliary dyskinesia and MMAF phenotype.Journal of human genetics · 2020Article
- Genetic disorders and male infertility.Reproductive medicine and biology · 2020Review
- A DNAH17 missense variant causes flagella destabilization and asthenozoospermia.The Journal of experimental medicine · 2020Article
- Male Infertility Diagnosis: Improvement of Genetic Analysis Performance by the Introduction of Pre-Diagnostic Genes in a Next-Generation Sequencing Custom-Made Panel.Frontiers in endocrinology · 2020Article
- Microtubular Dysfunction and Male Infertility.The world journal of men's health · 2020Review
- Ultrastructural Sperm Flagellum Defects in a Patient WithFrontiers in genetics · 2020Article
- Biallelic mutations inJournal of medical genetics · 2019Article
- New insights into the genetics of spermatogenic failure: a review of the literature.Human genetics · 2019Review
- Ran-binding protein M is associated with human spermatogenesis and oogenesis.Molecular medicine reports · 2018Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary ciliary dyskinesia (PCD) is an autosomal-recessive disorder resulting from the loss of normal ciliary function. Symptoms include neonatal respiratory distress, chronic sinusitis, bronchiectasis, situs inversus, and infertility. However, only 15 PCD-associated genes have been identified to cause male infertility to date. Owing to the genetic heterogeneity of PCD, comprehensive molecular genetic testing is not considered the standard of care. Here, we provide an update of the progress on the identification of genetic factors related to PCD associated with male infertility, summarizing the underlying molecular mechanisms, and discuss the clinical implications of these findings. Further research in this field will impact the diagnostic strategy for male infertility, enabling clinicians to provide patients with informed genetic counseling, and help to adopt the best course of treatment for developing directly targeted personalized medicine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.