Evidence map›Paper›PMID 27270185›Full record

ArticleJournal of hypertension2016

Cannabis use and blood pressure levels: United States National Health and Nutrition Examination Survey, 2005-2012.

Omayma Alshaarawy, Hosam A Elbaz

Abstract read
In one paragraph

Article in Journal of hypertension, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. The genetics of cannabis lifetime use.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Observational
  6. Review
  7. Endocannabinoid signaling in stress, nausea, and vomiting.Neurogastroenterology and motility · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. A Review of the Effects of Adolescent Cannabis Use on Physical Health.The Psychiatric clinics of North America · 2023
    Review
  16. Article
  17. Observational
  18. Article
  19. Article
  20. A Review of the Effects of Adolescent Cannabis Use on Physical Health.Child and adolescent psychiatric clinics of North America · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Omayma AlshaarawyaDepartment of Epidemiology and Biostatistics, Indiana University, Bloomington, Indiana bDepartment of Epidemiology and Biostatistics, Michigan State University, East Lansing, Michigan cDepartment of Biotechnology, Ivy Tech Community College, Bloomington, Indiana, USA.
Hosam A Elbaz

Funding

Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
Using pre-clinical biomarkers and epidemiological models to assess the effects of cannabinoids on diseaseR00AT009156 · NCCIH · MICHIGAN STATE UNIVERSITY · PI ALSHAARAWY, OMAYMA O · 2018 to 2020
$744k
Using pre-clinical biomarkers and epidemiological models to assess the effects of cannabinoids on diseaseK99AT009156 · NCCIH · MICHIGAN STATE UNIVERSITY · PI ALSHAARAWY, OMAYMA O · 2016 to 2017
$181k
NCATS NIH HHS UL1 TR001108NCCIH NIH HHS K99 AT009156NCCIH NIH HHS R00 AT009156
6 · The paper itself

Abstract

objectivePreclinical studies have reported acute cardiovascular effects of cannabis, including a dose-dependent increase in blood pressure (BP), whereas orthostatic hypotension may follow as a result of decreased vascular resistance. In case reports, evidence links cannabis with acute cardiovascular events in young and middle-aged adults. Here, we offer epidemiologic estimates on cannabis use and BP levels association from the US National Health and Nutrition Examination Surveys 2005-2012 (n = 12 426).

methodsComputer-assisted self-interviews assessed cannabis use. BP was determined by an average of up to four measurements taken during a single examination. Regression modeling was used to examine cannabis use and BP association.

resultsRecently active cannabis use was associated with increase in SBP (β = 1.6; 95% confidence interval: 0.6, 2.7) in the age-sex-adjusted model. Additional covariate adjustment did not affect the positive association. No association between cannabis use and DBP was detected.

conclusionA modest association between recent cannabis use and SBP was detected among a relatively large nationally representative sample of US adults. With the legalization of cannabis, there is a need for preclinical, clinical and prospective population-based research on the cardiovascular effects of cannabis use.

Indexed as

Blood PressureAdultBlood Pressure DeterminationFemaleHumansMaleMarijuana SmokingMiddle AgedNutrition SurveysProspective StudiesSubstance-Related DisordersSystoleUnited StatesYoung Adult

Identifiers

PMID27270185
PMCPMC5237375

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.