Evidence map›Paper›PMID 27270110›Full record

ArticleNutrition & diabetes2016

Plasma concentrations of coffee polyphenols and plasma biomarkers of diabetes risk in healthy Japanese women.

A H Lee, L 'b Tan, N Hiramatsu, A Ishisaka, H Alfonso, A Tanaka, N Uemura, Y Fujiwara, R Takechi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrition & diabetes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

A H LeeSchool of Public Health, Faculty of Health Sciences, Curtin University, Perth, Western Australia, Australia.
L 'b TanSchool of Public Health, Faculty of Health Sciences, Curtin University, Perth, Western Australia, Australia.
N HiramatsuSchool of Human Science and Environment, University of Hyogo, Himeji, Japan.
A IshisakaSchool of Human Science and Environment, University of Hyogo, Himeji, Japan.
H AlfonsoSchool of Public Health, Faculty of Health Sciences, Curtin University, Perth, Western Australia, Australia.
A TanakaNutrition Clinic, Kagawa Nutrition University, Tokyo, Japan.
N UemuraSchool of Human Science and Environment, University of Hyogo, Himeji, Japan.
Y FujiwaraSchool of Human Science and Environment, University of Hyogo, Himeji, Japan.
R TakechiSchool of Public Health, Faculty of Health Sciences, Curtin University, Perth, Western Australia, Australia.ORCID http://orcid.org/0000-0001-6359-3382
University of Hyogo · JPCurtin University · AUKagawa Nutrition University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coffee consumption has been reported to reduce the risk of type 2 diabetes in experimental and epidemiological studies. This anti-diabetic effect of coffee may be attributed to its high content in polyphenols especially caffeic acid and chlorogenic acid. However, the association between plasma coffee polyphenols and diabetic risks has never been investigated in the literature. In this study, fasting plasma samples were collected from 57 generally healthy females aged 38-73 (mean 52, s.d. 8) years recruited in Himeji, Japan. The concentrations of plasma coffee polyphenols were determined by liquid chromatography coupled with mass tandem spectrometer. Diabetes biomarkers in the plasma/serum samples were analysed by a commercial diagnostic laboratory. Statistical associations were assessed using Spearman's correlation coefficients. The results showed that plasma chlorogenic acid exhibited negative associations with fasting blood glucose, glycated hemoglobin and C-reactive protein, whereas plasma total coffee polyphenol and plasma caffeic acid were weakly associated with these biomarkers. Our preliminary data support previous findings that coffee polyphenols have anti-diabetic effects but further replications with large samples of both genders are recommended.

Indexed as

CoffeeAdultAgedBiomarkersCaffeic AcidsChlorogenic AcidC-Reactive ProteinDiabetes Mellitus, Type 2FemaleGlycated HemoglobinHumansMiddle AgedRiskBiomarkerscaffeic acidCaffeic AcidsChlorogenic AcidCoffeeC-Reactive ProteinGlycated Hemoglobinhemoglobin A1c protein, human

Identifiers

PMID27270110
PMCPMC4931312
OpenAlexW2410742416

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.