Evidence map›Paper›PMID 27269963›Full record

SynthesisHuman vaccines & immunotherapeutics2016

Epidemiology of community-acquired pneumonia and implications for vaccination of children living in developing and newly industrialized countries: A systematic literature review.

Rodrigo DeAntonio, Juan-Pablo Yarzabal, James Philip Cruz, Johannes E Schmidt, Jos Kleijnen

Abstract readSystematic Review
In one paragraph

Synthesis in Human vaccines & immunotherapeutics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Risk factors for severeFrontiers in pediatrics · 2026
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  11. [Distribution of non-bacterial pathogens in 1 788 children with community-acquired pneumonia].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rodrigo DeAntonioa GSK Vaccines, Ciudad del Saber , Panama.
Juan-Pablo Yarzabalb GSK Vaccines , Wavre , Belgium.
James Philip Cruzc GSK Vaccines , Singapore.
Johannes E Schmidtb GSK Vaccines , Wavre , Belgium.
Jos Kleijnend School for Public Health and Primary Care (CAPHRI), Maastricht University , Maastricht , The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This systematic review evaluated the epidemiology of community-acquired pneumonia in children <6 y of age within 90 developing and newly industrialized countries. Literature searches (1990-2011), based on MEDLINE, EMBASE, Cochrane, CAB Global Health, WHO, UNICEF, country-specific websites, conferences, health-technology-assessment agencies, and the reference lists of included studies, yielded 8,734 records; 62 of 340 studies were included in this review. The highest incidence rate among included studies was 0.51 episodes/child-year, for children <5 y of age in Bangladesh. The highest prevalence was in Chinese children <6 months of age (37.88%). The main bacterial pathogens were Streptococcus pneumoniae, Haemophilus influenzae and Mycoplasma pneumoniae and the main viral pathogens were respiratory syncytial virus, adenovirus and rhinovirus. Community-acquired pneumonia remains associated with high rates of morbidity and mortality. Improved and efficient surveillance and documentation of the epidemiology and burden of community-acquired pneumonia across various geographical regions is warranted.

Indexed as

BacteriaChild, PreschoolCommunity-Acquired InfectionsDeveloped CountriesDeveloping CountriesHumansIncidenceInfantInfant, NewbornPneumonia, BacterialPneumonia, ViralPrevalenceVirusesAfricachildrenChinacommunity-acquired pneumoniaepidemiologyIndia and South AsiaMiddle EastRussia and the Commonwealth of Independent Statessystematic review

Identifiers

PMID27269963
PMCPMC5027706

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.