Evidence map›Paper›PMID 27269298›Full record

ArticlePublic health nutrition2016

Physical impairment and body weight history in postmenopausal women: the Women's Health Initiative.

Amal A Wanigatunga, Sandrine S Sourdet, Michael J LaMonte, Molly E Waring, Rami Nassir, Lorena Garcia, Jennifer W Bea, Rebecca A Seguin, Judith K Ockene, Gloria E Sarto and 4 more

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In one paragraph

Article in Public health nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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  3. Article
  4. Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Amal A Wanigatunga1Department of Epidemiology,University of Florida,2004 Mowry Road,Cubicle 2148-C4,Gainesville,FL 32608,USA.
Sandrine S Sourdet3Internal Medicine Service and Gerontology Clinic,Toulouse,France.
Michael J LaMonte4Department of Epidemiology and Environmental Health,University of Buffalo,Buffalo,NY,USA.
Molly E Waring5Department of Quantitative Health Sciences,University of Massachusetts,Worcester,MA,USA.
Rami Nassir7Department of Biochemistry and Molecular Medicine,University of California Davis,Davis,CA,USA.
Lorena Garcia8Department of Public Health Sciences,University of California Davis,Davis,CA,USA.
Jennifer W Bea9Department of Nutritional Sciences,University of Arizona,Tucson,AZ,USA.
Rebecca A Seguin10Division of Nutritional Sciences,Cornell University,Ithaca,NY,USA.
Judith K Ockene11Division of Preventive and Behavioral Medicine,University of Massachusetts,Worcester,MA,USA.
Gloria E Sarto12Department of Obstetrics and Gynecology,University of Wisconsin,Madison,WI,USA.
Marcia L Stefanick13Standford Prevention Research Center,Stanford University,Stanford,CA,USA.
Marian Limacher14Department of Medicine,University of Florida,Gainesville,FL,USA.
Todd M Manini2Department of Aging & Geriatric Research,Institute on Aging,University of Florida,Gainesville,FL,USA.
Women’s Health Initiative Investigators

Funding

Translational Oncology Research Program (Project-005)P30CA124435 · NCI · STANFORD UNIVERSITY · PI Melinda L. Telli · 2007 to 2026
$71.4M
University of Massachusetts Center for Clinical Science and Translational SupplementUL1TR001453 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2015 to 2024
$39.0M
University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI CHRISTIAAN LEEUWENBURGH · 2007 to 2026
$22.8M
TRACE-COREU01HL105268 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI KIEFE, CATARINA I. · 2010 to 2013
$5.8M
Osteoporotic Fractures in MenU01AR045583 · NIAMS · STANFORD UNIVERSITY · PI STEFANICK, MARCIA L. · 1999 to 2011
$4.0M
University of Massachusetts Center for Clinical and Translational ScienceKL2TR000160 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2012 to 2014
$1.7M
Metabolic Costs of Daily Activities in Older AdultsR01AG042525 · NIA · UNIVERSITY OF FLORIDA · PI MANINI, TODD · 2013 to 2017
$1.6M
CLIN CTR CLIN TRIAL/OBSERVATIONAL STUDY OF WHIN01WH042109 · WH · STANFORD UNIVERSITY · PI STEFANICK, MARCIA L · 1994 to 2000
$1.4M
CLIN CTR CLIN TRIAL/OBSERVATIONAL STUDY OF WHIN01WH042129 · WH · UNIVERSITY OF FLORIDA · PI LIMACHER, MARIAN C. · 1994 to 2000
$868k
METABOLIC SYNDROME AND PERIODONTITIS IN POSTMENOPAUSAL WOMENR03DE022654 · NIDCR · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI LAMONTE, MICHAEL J · 2012 to 2013
$311k
NCATS NIH HHS KL2 TR000160NCATS NIH HHS UL1 TR001453NCI NIH HHS P30 CA124435NHLBI NIH HHS HHSN268201100001INHLBI NIH HHS HHSN268201100002INHLBI NIH HHS HHSN268201100003INHLBI NIH HHS HHSN268201100004INHLBI NIH HHS HHSN268201100046CNHLBI NIH HHS U01 HL105268NIAMS NIH HHS U01 AR045583NIA NIH HHS P30 AG028740NIA NIH HHS R01 AG042525NIDCR NIH HHS R03 DE022654WHI NIH HHS HHSN268201100001CWHI NIH HHS HHSN268201100002CWHI NIH HHS HHSN268201100003CWHI NIH HHS HHSN268201100004CWHI NIH HHS N01 WH042109WHI NIH HHS N01 WH042129
6 · The paper itself

Abstract

objectiveTo examine whether weight history and weight transitions over adult lifespan contribute to physical impairment among postmenopausal women.

designBMI categories were calculated among postmenopausal women who reported their weight and height at age 18 years. Multiple-variable logistic regression was used to determine the association between BMI at age 18 years and BMI transitions over adulthood on severe physical impairment (SPI), defined as scoring <60 on the Physical Functioning subscale of the Rand thirty-six-item Short-Form Health Survey.

settingParticipants were part of the Women's Health Initiative Observational Study (WHI OS), where participants' health was followed over time via questionnaires and clinical assessments. SUBJECTS: Postmenopausal women (n 76 016; mean age 63·5 (sd 7·3) years).

resultsWomen with overweight (BMI=25·0-29·9 kg/m2) or obesity (BMI≥30·0 kg/m2) at 18 years had greater odds (OR (95 % CI)) of SPI (1·51 (1·35, 1·69) and 2·14 (1·72, 2·65), respectively) than normal-weight (BMI=18·5-24·9 kg/m2) counterparts. Transitions from normal weight to overweight/obese or to underweight (BMI<18·5 kg/m2) were associated with greater odds of SPI (1·97 (1·84, 2·11) and 1·35 (1·06, 1·71), respectively) compared with weight stability. Shifting from underweight to overweight/obese also had increased odds of SPI (1·52 (1·11, 2·09)). Overweight/obese to normal BMI transitions resulted in a reduced SPI odds (0·52 (0·39, 0·71)).

conclusionsHigher weight history and transitions into higher weight classes were associated with higher likelihood of SPI, while transitioning into lower weight classes for those with overweight/obesity was protective among postmenopausal women.

Indexed as

Body WeightMobility LimitationPostmenopauseAgedBody Mass IndexFemaleHealth StatusHumansMiddle AgedObesityOverweightRisk FactorsWomen's HealthBMIBody weightDisabilityPhysical functionPhysical impairmentWeight change

Identifiers

PMID27269298
PMCPMC5135627

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.