ArticleBMC ophthalmology2016
Biometry and visual function of a healthy cohort in Leipzig, Germany.
Article in BMC ophthalmology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01173614 (Project Gullstrand - European Project for the Determination of Average Biometric Values of Human Eyes), which is not on this map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Project Gullstrand - European Project for the Determination of Average Biometric Values of Human Eyes
Who cites it
11 citing papers in PubMed.
- Importance of Type and Direction of Eyelid Sliding to Mimic Blinking In Vitro for Dry Eye Disease and Contact Lens Research.Investigative ophthalmology & visual science · 2026Article
- Assessment of factors affecting anterior chamber depth from data obtained from health checkup participants in Japan.Scientific reports · 2024Article
- Associations between corneal curvature and other anterior segment biometrics in young myopic adults.Scientific reports · 2024Article
- Distribution of Axial Length in Australians of Different Age Groups, Ethnicities, and Refractive Errors.Translational vision science & technology · 2023Article
- Key Factors in Early Diagnosis of Myopia Progression within Ocular Biometric Parameters by Scheimpflug Technology.Life (Basel, Switzerland) · 2023Article
- Uncorrected refractive errors are important causes of avoidable visual impairment in Hungary: re-evaluation of two existing national data sets.International journal of ophthalmology · 2023Article
- Prevalence of refractive errors in Hungary reveals three-fold increase in myopia.International journal of ophthalmology · 2022Article
- Evaluation of ocular biometry in the Japanese population using a multicenter approach: Prospective observational study.PloS one · 2022Observational
- Refractive error and biometrics of anterior segment of eyes of healthy young university students in Japan.Scientific reports · 2019Article
- Ophthalmologic health status of an aging population-data from the Berlin Aging Study II (BASE-II).Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019Article
- Evaluation of the precision of contrast sensitivity function assessment on a tablet device.Scientific reports · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCross-sectional survey of ocular biometry and visual function in healthy eyes across the life span of a German population aged 20 to 69 years (n = 218). Subject number in percent per age category reflected the percentage within the respective age band of the population of Leipzig, Germany.
methodsMeasurements obtained: subjective and objective refraction, best-corrected visual acuity, accommodation, contrast sensitivity, topography and pachymetry with Scheimpflug camera, axial length with non-contact partial coherence interferometry, and spectral-domain optical coherence tomography of the retina. Pearson correlation coefficients with corresponding p-values were given to present interrelationships between stature, biometric and refractive parameters or their associations with age. Two-sample T-tests were used to calculate gender differences. The area under the logarithmic contrast sensitivity function (AULCSF) was calculated for the analysis of contrast sensitivity as a single figure across a range of spatial frequencies.
resultsThe results of axial length (AL), anterior chamber depth (ACD) and anterior chamber volume (ACV) differed as a function of the age of the participants (rho (p value): AL -0.19 (0.006), ACD -0.56 (< 0.001), ACV-0.52 (< 0.001)). Longer eyes had deeper ACD (AL:ACD 0.62 (< 0.001), greater ACV (AL:ACV 0.65 (< 0.001) and steeper corneal radii (AL:R1ant; R2ant; R1post; R2post 0.40; 0.35; 0.36; 0.36 (all with (< 0.001)). Spherical equivalent was associated with age (towards hyperopia: 0.34 (< 0.001)), AL (-0.66 (< 0.001)), ACD (-0.52 (< 0.001)) and ACV (-0.46 (< 0.001)). Accommodation was found lower for older subjects (negative association with age, r = -0.82 (< 0.001)) and contrast sensitivity presented with smaller values for older ages (AULCSF -0.38, (< 0.001)), no change of retinal thickness with age. 58 % of the study cohort presented with a change of refractive correction above ±0.50 D in one or both eyes (64 % of these were habitual spectacle wearers), need for improvement was present in the young age-group and for older subjects with increasing age.
conclusionBiometrical data of healthy German eyes, stratified by age, gender and refractive status, enabled cross-comparison of all parameters, providing an important reference database for future patient-based research and specific in-depth investigations of biometric data in epidemiological research.
trial registrationClinicalTrials.gov # NCT01173614 July 28, 2010.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.