Evidence map›Paper›PMID 27268121›Full record

ReviewExpert review of molecular diagnostics2016

Biological markers of prognosis, response to therapy and outcome in ovarian carcinoma.

Marta Szajnik, Małgorzata Czystowska-Kuźmicz, Esther Elishaev, Theresa L Whiteside

Open access · greenAbstract readReview
In one paragraph

Review in Expert review of molecular diagnostics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
7.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Exosomes in Cancer: Diagnostic and Therapeutic Applications.Clinical Medicine Insights. Oncology · 2024
    Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Regulation of angiogenesis by microRNAs in cancer.Molecular medicine reports · 2021
    Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Marta Szajnika Department of Gynecology and Gynecologic Oncology , Military Institute of Medicine , Warsaw , Poland.
Małgorzata Czystowska-Kuźmiczb Department of Immunology, Centre of Biostructure Research , Medical University of Warsaw , Warsaw , Poland.
Esther Elishaevc Department of Pathology , University of Pittsburgh, School of Medicine , Pittsburgh , PA , USA.
Theresa L Whitesidec Department of Pathology , University of Pittsburgh, School of Medicine , Pittsburgh , PA , USA.
Medical University of Warsaw · PLUniversity of Pittsburgh · US

Funding

Restoring anti-tumor immunity in the microenvironment of head and neck cancerR01CA168628 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WHITESIDE, THERESA L. · 2013 to 2017
$1.7M
NCI NIH HHS R01 CA168628
6 · The paper itself

Abstract

introductionOvarian cancer (OvCa) is among the most common types of cancer and is the leading cause of death from gynecological malignancies in western countries. Cancer biomarkers have a potential for improving the management of OvCa patients at every point from screening and detection, diagnosis, prognosis, follow up, response to therapy and outcome. AREAS COVERED: The literature search has indicated a number of candidate biomarkers have recently emerged that could facilitate the molecular definition of OvCa, providing information about prognosis and predicting response to therapy. These potentially promising biomarkers include immune cells and their products, tumor-derived exosomes, nucleic acids and epigenetic biomarkers. Expert commentary: Although most of the biomarkers available today require prospective validation, the development of noninvasive liquid biopsy-based monitoring promises to improve their utility for evaluations of prognosis, response to therapy and outcome in OvCa.

Indexed as

Biomarkers, TumorCA-125 AntigenCarcinomaCombined Modality TherapyEpigenesis, GeneticExosomesFemaleHumansMembrane ProteinsMicroRNAsNeoplastic Stem CellsOvarian NeoplasmsPrognosisProteinsTreatment OutcomeWAP Four-Disulfide Core Domain Protein 2Biomarkers, TumorCA-125 AntigenMembrane ProteinsMicroRNAsMUC16 protein, humanProteinsWAP Four-Disulfide Core Domain Protein 2WFDC2 protein, humanexosomesimmune biomarkersmicroRNAsOvarian carcinomaserumtissue

Identifiers

PMID27268121
PMCPMC5010004
OpenAlexW2417452526

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.