ArticleMechanisms of ageing and development2016
Does cytomegalovirus infection contribute to socioeconomic disparities in all-cause mortality?
Article in Mechanisms of ageing and development, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed.
- Correspondence Between Cytomegalovirus Immunoglobulin-G Levels Measured in Saliva and Serum.Frontiers in immunology · 2020Trial
- Health impact of a hypothetical intervention on immune burden of cytomegalovirus (CMV) among older adults in the US: a prospective analysis of the Health and Retirement Study Cohort.Lancet regional health. Americas · 2025Article
- Human leukocyte antigen variation is associated with cytomegalovirus serostatus in healthy individuals.American journal of human genetics · 2025Article
- Association between cytomegalovirus infection and dyslipidemia in US: an NHANES analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024Article
- The Association of Cytomegalovirus and Allostatic Load by Country of Birth and Length of Time in the United States.Diseases (Basel, Switzerland) · 2023Article
- Socioeconomic and race/ethnic differences in immunosenescence: Evidence from the Health and Retirement Study.Brain, behavior, and immunity · 2023Article
- Sociodemographic Differences in Population-Level Immunosenescence in Older Age.medRxiv : the preprint server for health sciences · 2022Article
- Understanding the interaction between cytomegalovirus and tuberculosis in children: The way forward.PLoS pathogens · 2021Review
- The Association Between Cytomegalovirus and Disability by Race/Ethnicity and Sex: Results From the Health and Retirement Study.American journal of epidemiology · 2021Article
- Life Course Socioeconomic Disadvantage and the Aging Immune System: Findings From the Health and Retirement Study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2021Article
- High cytomegalovirus serology and subsequent COPD-related mortality: a longitudinal study.ERJ open research · 2020Article
- Race/Ethnic and Educational Disparities in the Association Between Pathogen Burden and a Laboratory-Based Cumulative Deficits Index.Journal of racial and ethnic health disparities · 2020Article
- Persistent socioeconomic and racial and ethnic disparities in pathogen burden in the United States, 1999-2014.Epidemiology and infection · 2019Article
- 'From immunosenescence to immune modulation': a re-appraisal of the role of cytomegalovirus as major regulator of human immune function.Medical microbiology and immunology · 2019Review
- How does cytomegalovirus factor into diseases of aging and vaccine responses, and by what mechanisms?GeroScience · 2017Article
- Does Regular Exercise Counter T Cell Immunosenescence Reducing the Risk of Developing Cancer and Promoting Successful Treatment of Malignancies?Oxidative medicine and cellular longevity · 2017Review
- Cytomegalovirus vaccines under clinical development.Journal of virus eradication · 2016Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
The social patterning of cytomegalovirus (CMV) and its implication in aging suggest that the virus may partially contribute to socioeconomic disparities in mortality. We used Cox regression and inverse odds ratio weighting to quantify the proportion of the association between socioeconomic status (SES) and all-cause mortality that was attributable to mediation by CMV seropositivity. Data were from the National Health and Nutrition Examination Survey (NHANES) III (1988-1994), with mortality follow-up through December 2011. SES was assessed as household income (income-to-poverty ratio ≤1.30;>1.30 to≤1.85;>1.85 to≤3.50;>3.50) and education (<high school; high school; >high school). We found strong associations between low SES and increased mortality: hazard ratio (HR) 1.80; 95% confidence interval (CI): 1.57, 2.06 comparing the lowest versus highest income groups and HR 1.29; 95% CI: 1.13, 1.48 comparing <high school versus >high school education. 65% of individuals were CMV seropositive, accounting for 6-15% of the SES-mortality associations. Age modified the associations between SES, CMV, and mortality, with CMV more strongly associated with mortality in older individuals. Our findings suggest that cytomegalovirus may partially contribute to persistent socioeconomic disparities in mortality, particularly among older individuals.
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