Evidence map›Paper›PMID 27267963›Full record

ReviewGigaScience2016

Recommendations on e-infrastructures for next-generation sequencing.

Ola Spjuth, Erik Bongcam-Rudloff, Johan Dahlberg, Martin Dahlö, Aleksi Kallio, Luca Pireddu, Francesco Vezzi, Eija Korpelainen

Abstract readReview
In one paragraph

Review in GigaScience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Deep Learning in Image Cytometry: A Review.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2019
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. MGIS: managing banana (Musa spp.) genetic resources information and high-throughput genotyping data.Database : the journal of biological databases and curation · 2017
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ola SpjuthDepartment of Pharmaceutical Biosciences and Science for Life Laboratory, Uppsala University, Uppsala, P.O. Box 591, SE-75124, Sweden. ola.spjuth@farmbio.uu.se.
Erik Bongcam-RudloffSLU-Global Bioinformatics Centre, Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Johan DahlbergNational Genomics Infrastructure, Science for Life Laboratory, Uppsala University, Stockholm, P.O. Box 1031, SE-17121, Sweden.
Martin DahlöDepartment of Pharmaceutical Biosciences and Science for Life Laboratory, Uppsala University, Uppsala, P.O. Box 591, SE-75124, Sweden.
Aleksi KallioCSC - IT Center for Science Ltd., Espoo, P.O. Box 405, FI-02101, Finland.
Luca PiredduCRS4, Polaris, Loc. Piscina Manna Ed. 1, Pula, 09010, Italy.
Francesco VezziScience for Life Laboratory, Stockholm University, Stockholm, SE-17121, Sweden.
Eija KorpelainenCSC - IT Center for Science Ltd., Espoo, P.O. Box 405, FI-02101, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With ever-increasing amounts of data being produced by next-generation sequencing (NGS) experiments, the requirements placed on supporting e-infrastructures have grown. In this work, we provide recommendations based on the collective experiences from participants in the EU COST Action SeqAhead for the tasks of data preprocessing, upstream processing, data delivery, and downstream analysis, as well as long-term storage and archiving. We cover demands on computational and storage resources, networks, software stacks, automation of analysis, education, and also discuss emerging trends in the field. E-infrastructures for NGS require substantial effort to set up and maintain over time, and with sequencing technologies and best practices for data analysis evolving rapidly it is important to prioritize both processing capacity and e-infrastructure flexibility when making strategic decisions to support the data analysis demands of tomorrow. Due to increasingly demanding technical requirements we recommend that e-infrastructure development and maintenance be handled by a professional service unit, be it internal or external to the organization, and emphasis should be placed on collaboration between researchers and IT professionals.

Indexed as

Computational BiologyHigh-Throughput Nucleotide SequencingHumansInformation Storage and RetrievalInternetSequence Analysis, DNASoftwareCloud computingE-infrastructureHigh-performance computingNext-generation sequencing

Identifiers

PMID27267963
PMCPMC4897895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.