Evidence map›Paper›PMID 27267926›Full record

ArticleGigaScience2016

Gigwa-Genotype investigator for genome-wide analyses.

Guilhem Sempéré, Florian Philippe, Alexis Dereeper, Manuel Ruiz, Gautier Sarah, Pierre Larmande

Erratum issuedAbstract read
In one paragraph

Article in GigaScience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  8. Benchmarking database systems for Genomic Selection implementation.Database : the journal of biological databases and curation · 2019
    Article
  9. Article
  10. MGIS: managing banana (Musa spp.) genetic resources information and high-throughput genotyping data.Database : the journal of biological databases and curation · 2017
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Guilhem SempéréUMR InterTryp (CIRAD), Campus International de Baillarguet, 34398, Montpellier, Cedex 5, France. guilhem.sempere@cirad.fr.
Florian PhilippeUMR DIADE (IRD), 911 Avenue Agropolis, 34934, Montpellier, Cedex 5, France.
Alexis DereeperSouth Green Bioinformatics Platform, 1000 Avenue Agropolis, 34934, Montpellier, Cedex 5, France.
Manuel RuizSouth Green Bioinformatics Platform, 1000 Avenue Agropolis, 34934, Montpellier, Cedex 5, France.
Gautier SarahSouth Green Bioinformatics Platform, 1000 Avenue Agropolis, 34934, Montpellier, Cedex 5, France.
Pierre LarmandeSouth Green Bioinformatics Platform, 1000 Avenue Agropolis, 34934, Montpellier, Cedex 5, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExploring the structure of genomes and analyzing their evolution is essential to understanding the ecological adaptation of organisms. However, with the large amounts of data being produced by next-generation sequencing, computational challenges arise in terms of storage, search, sharing, analysis and visualization. This is particularly true with regards to studies of genomic variation, which are currently lacking scalable and user-friendly data exploration solutions. DESCRIPTION: Here we present Gigwa, a web-based tool that provides an easy and intuitive way to explore large amounts of genotyping data by filtering it not only on the basis of variant features, including functional annotations, but also on genotype patterns. The data storage relies on MongoDB, which offers good scalability properties. Gigwa can handle multiple databases and may be deployed in either single- or multi-user mode. In addition, it provides a wide range of popular export formats.

conclusionsThe Gigwa application is suitable for managing large amounts of genomic variation data. Its user-friendly web interface makes such processing widely accessible. It can either be simply deployed on a workstation or be used to provide a shared data portal for a given community of researchers.

Indexed as

Computational BiologyDatabases, GeneticGenetic VariationGenome-Wide Association StudyGenotypeInformation Storage and RetrievalInternetSequence Analysis, DNASoftwareUser-Computer InterfaceGenomic variationsHapMapINDELMongoDBNoSQLSNPVCFWeb interface

Identifiers

PMID27267926
PMCPMC4897896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.