Evidence map›Paper›PMID 27267897›Full record

ArticleBMC psychiatry2016

The relationship between self-reported mental health and redeemed prescriptions of antidepressants: a register-based cohort study.

Louise Sjørslev Frandsen, Line Bilgrav Villumsen, Cathrine Fonnesbech Hjorth, Berit Jamie Nielsen, Line Rosenkilde Ullits, Christian Torp-Pedersen, Henrik Bøggild, Charlotte Overgaard

Open access · goldAbstract read
In one paragraph

Article in BMC psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Louise Sjørslev FrandsenPublic Health and Epidemiology Group, Department of Health Science and Technology, Aalborg University, Niels Jernes Vej 14, DK-9220, Aalborg, Denmark. guddifrandsen@hotmail.com.
Line Bilgrav VillumsenPublic Health and Epidemiology Group, Department of Health Science and Technology, Aalborg University, Niels Jernes Vej 14, DK-9220, Aalborg, Denmark.
Cathrine Fonnesbech HjorthPublic Health and Epidemiology Group, Department of Health Science and Technology, Aalborg University, Niels Jernes Vej 14, DK-9220, Aalborg, Denmark.
Berit Jamie NielsenDepartment of Clinical Epidemiology, Aalborg University Hospital, Sdr. Skovvej 15, DK-9000, Aalborg, Denmark.
Line Rosenkilde UllitsPublic Health and Epidemiology Group, Department of Health Science and Technology, Aalborg University, Niels Jernes Vej 14, DK-9220, Aalborg, Denmark.
Christian Torp-PedersenPublic Health and Epidemiology Group, Department of Health Science and Technology, Aalborg University, Niels Jernes Vej 14, DK-9220, Aalborg, Denmark.
Henrik BøggildPublic Health and Epidemiology Group, Department of Health Science and Technology, Aalborg University, Niels Jernes Vej 14, DK-9220, Aalborg, Denmark.
Charlotte OvergaardPublic Health and Epidemiology Group, Department of Health Science and Technology, Aalborg University, Niels Jernes Vej 14, DK-9220, Aalborg, Denmark.
Aalborg University · DKAalborg University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPoor mental health is a major problem in most western societies, especially predominant among young adults. However, associations of self-reported poor mental health with subsequent psychiatric or medical treatment are unknown. We examined the relation between self-reported mental health and redeeming prescriptions of antidepressants among three age groups.

methodsWe analyzed data from 16,233 individuals aged 16 years and over randomly selected to participate in the 2010 North Denmark Region Health Survey completed in February 2010. Mental health was defined according to the Short-Form 12 instrument (SF-12) and dichotomized into poor and good. Outcome data were retrieved from administrative information on redeemed prescriptions of antidepressants between February 2010 and December 2012. Crude cumulative incidence curves were produced to illustrate the probability of redeeming new prescriptions of antidepressants over time. Cox regression analysis was used to estimate risk of redeeming prescriptions of antidepressants when having poor mental health, adjusted for preselected explanatory covariates.

resultsAmong the young (16-29 years-old), 620 (23 %) participants suffered from poor mental health. Among the adults (30-59 years-old) and elderly (60 years-old or over), 1592 (18 %) participants and 723 (15 %) reported poor mental health, respectively. Overall, women were more likely than men to rate their mental health as poor. For all age groups, there was an increased probability for redeeming prescriptions of antidepressants when having poor mental health. The hazard ratio [HR] for redeeming prescriptions of antidepressants for those reporting poor versus good mental health, adjusted for sex, ethnicity, marital status, education level, occupational status, smoking and physical activity was 3.1 (95 % confidence interval [CI] 2.20-4.29) for young participants. For adults, the HR was 2.3 (95 % CI 1.86-2.78) and for elderly, it was 3.5 (95 % CI 2.66-4.57).

conclusionSelf-reported poor mental health was more frequent among younger than older participants. Overall, antidepressants were the most often used treatment. An increased probability of redeeming antidepressant prescriptions when having self-reported poor mental health was observed in all age groups. These findings suggest that frequent reporting of poor mental health is a common issue for all age groups that needs more attention.

Indexed as

AdolescentAdultAgedAntidepressive AgentsCohort StudiesDenmarkFemaleHumansMaleMental DisordersMental HealthMiddle AgedProportional Hazards ModelsRisk FactorsSelf ReportYoung AdultAntidepressive AgentsAntidepressant agentsMental healthSex differencesYoung

Identifiers

PMID27267897
PMCPMC4897872
OpenAlexW2417851199

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.