Evidence map›Paper›PMID 27267684›Full record

ArticleNeuropharmacology2017

Repeated ventral midbrain neurotensin injections sensitize to amphetamine-induced locomotion and ERK activation: A role for NMDA receptors.

David Voyer, Daniel Lévesque, Pierre-Paul Rompré

Open access · greenAbstract read
In one paragraph

Article in Neuropharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

David VoyerFaculty of Pharmacy, Université de Montréal, Montreal, Quebec, Canada.
Daniel LévesqueFaculty of Pharmacy, Université de Montréal, Montreal, Quebec, Canada.
Pierre-Paul RompréDepartment of Neurosciences, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada; FRQ-S Research Group in Behavioral Neurobiology, Concordia University, Montréal, Quebec, Canada. Electronic address: pierre-paul.rompre@umontreal.ca.
Université de Montréal · CA

Funding

CIHR 130407-1Wellcome Trust 102572
6 · The paper itself

Abstract

Previous studies have shown that activation of ventral midbrain NMDA receptors is required to initiate sensitization by amphetamine. In view of the recent evidence that neurotensin modulates ventral midbrain glutamate neurotransmission, we tested the hypothesis that neurotensin is acting upstream to glutamate to initiate sensitization to the behavioral and neurochemical effects of amphetamine. During a first testing phase, adult male rats implanted with bilateral ventral midbrain cannulae were injected every second day for three days with D-[Tyr

Indexed as

AmphetamineAnimalsMaleMesencephalonMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3Motor ActivityNeuronsNeurotensinNucleus AccumbensPrefrontal CortexRatsRats, Long-EvansReceptors, N-Methyl-D-AspartateAmphetamineMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3NeurotensinReceptors, N-Methyl-D-AspartateAccumbensAmphetamineERKGlutamateNeurotensinPrefrontal cortexVentral midbrain

Identifiers

PMID27267684
PMCPMC5346307
OpenAlexW2411205833

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.