Evidence map›Paper›PMID 27267598›Full record

ArticleHealth and quality of life outcomes2016

Quality of life in patients with vitiligo: a cross-sectional study based on Vitiligo Quality of Life index (VitiQoL).

Kosar Hedayat, Mojgan Karbakhsh, Maryam Ghiasi, Azadeh Goodarzi, Yousef Fakour, Zahra Akbari, Afsaneh Ghayoumi, Narges Ghandi

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Article in Health and quality of life outcomes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. The humanistic burden of vitiligo: a systematic literature review of quality-of-life outcomes.Journal of the European Academy of Dermatology and Venereology : JEADV · 2022
    Pooled it
  2. Psychosocial Effects of Vitiligo: A Systematic Literature Review.American journal of clinical dermatology · 2021
    Pooled it
  3. Scoring Systems in Vitiligo-A Narrative Review.Indian dermatology online journal · 2026
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  19. Vitiligo prevalence and quality of life among adults in Europe, Japan and the USA.Journal of the European Academy of Dermatology and Venereology : JEADV · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kosar HedayatAutoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Mojgan KarbakhshDepartment of Community and Preventive Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Maryam GhiasiAutoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Azadeh GoodarziDepartment of Dermatology, Iran University of Medical Sciences, Tehran, Iran.
Yousef FakourDepartment of Psychology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Zahra AkbariAutoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Afsaneh GhayoumiAutoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Narges GhandiAutoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran. nghandi@tums.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVitiligo is a multi-factorial pigmentary skin disorder. Recently, the importance of emotional and psychological issues is proposed in incidence, progression, relapse and remission of vitiligo. There are limited studies conducted in developing countries, which assess life quality of patients with vitiligo. The aim of this study was the application and evaluation of a disease-specific quality of life index in Iranian patients, for the first time.

methodsThis cross-sectional biphasic study was conducted on 25 patients as a pilot and another 173 patients as the main study group, in Razi Hospital, Tehran, Iran, 2013-2014. Persian version of Vitiligo Quality of Life index (VitiQoL) was developed with backward-forward method. Based on the pilot study, the validity and reliability were assessed. The Vitiligo Area and Score Index (VASI), VitiQoL, and their relationship, demographic and clinical characteristic of patients were measured.

resultsThe Mean and standard deviation of the VitiQoL score was 30.5 ± 14.5 (range 0-60 in Persian version). There was a significant relationship between VASI score and VitiQoL (p = 0.015, r = 0.187). Confirmatory factor analysis revealed three important factors within VitiQoL: participation limitation, stigma, and behavior. In subscale analysis based on behavior factor, female patients had poorer quality of life (p = 0.02). Concomitant psychiatric problems, e.g. anxiety and depression, were not associated with QOL; however, they were near to being meaningful (p = 0.06, r = 0.14).

conclusionVitiQoL is a valid index in estimating life quality of vitiligo patients and has proper relation to disease severity. Focusing on patient's life quality is an important entity in the management of vitiligo patients; relevant supportive group-based consultations and therapies are also important arms when approaching vitiligo.

Indexed as

Quality of LifeAdolescentAdultAnalysis of VarianceAnxietyCross-Sectional StudiesDepressionFactor Analysis, StatisticalFemaleHumansIranMaleMiddle AgedPilot ProjectsReproducibility of ResultsSex FactorsIranQuality of lifeVASIVitiligoVitiligo area and score indexVitiligo quality of life instrumentVitiQoL

Identifiers

PMID27267598
PMCPMC4897932

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.