Evidence map›Paper›PMID 27267551›Full record

ArticleSurgery2016

Long-term effects of physical exercise during rehabilitation in patients with severe burns.

Paul Wurzer, Charles D Voigt, Robert P Clayton, Clark R Andersen, Ronald P Mlcak, Lars-P Kamolz, David N Herndon, Oscar E Suman

Abstract readControlled Clinical Trial
In one paragraph

Article in Surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Trial
  5. Trial
  6. Article
  7. Key Exercise Concepts in the Rehabilitation from Severe Burns.Physical medicine and rehabilitation clinics of North America · 2023
    Review
  8. Rehabilitative Exercise Training for Burn Injury.Sports medicine (Auckland, N.Z.) · 2021
    Review
  9. [Research advances on the effect of resistance training on the rehabilitation of burned children].Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns · 2021
    Review
  10. Article
  11. Cardiovascular Effect of Varying Interval Training Frequency in Rehabilitation of Severely Burned Children.Journal of burn care & research : official publication of the American Burn Association · 2019
    Article
  12. Rehabilitation Exercise Increases Physical Activity Levels in Severely Burned Children While Improving Aerobic Exercise Capacity and Strength.Journal of burn care & research : official publication of the American Burn Association · 2018
    Article
  13. Burn Injury May Have Age-Dependent Effects on Strength and Aerobic Exercise Capacity in Males.Journal of burn care & research : official publication of the American Burn Association · 2018
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Paul WurzerDepartment of Surgery, University of Texas Medical Branch and Shriners Hospitals for Children, Galveston, TX; Division of Plastic, Aesthetic and Reconstructive Surgery, Department of Surgery, Medical University of Graz, Graz, Austria.
Charles D VoigtDepartment of Surgery, University of Texas Medical Branch and Shriners Hospitals for Children, Galveston, TX.
Robert P ClaytonDepartment of Surgery, University of Texas Medical Branch and Shriners Hospitals for Children, Galveston, TX.
Clark R AndersenDepartment of Surgery, University of Texas Medical Branch and Shriners Hospitals for Children, Galveston, TX.
Ronald P MlcakDepartment of Respiratory Care, Shriners Hospitals for Children, Galveston, TX.
Lars-P KamolzDivision of Plastic, Aesthetic and Reconstructive Surgery, Department of Surgery, Medical University of Graz, Graz, Austria.
David N HerndonDepartment of Surgery, University of Texas Medical Branch and Shriners Hospitals for Children, Galveston, TX.
Oscar E SumanDepartment of Surgery, University of Texas Medical Branch and Shriners Hospitals for Children, Galveston, TX. Electronic address: oesuman@utmb.edu.

Funding

UTMB Clinical and Translational Science AwardUL1TR001439 · NCATS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI URBAN, RANDALL J · 2015 to 2024
$40.0M
Project 9: The role of androgen/corticosteroid in fat, muscle and glucose metabolism of burn victimsP50GM060338 · NIGMS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI SZABO, CSABA · 2000 to 2017
$24.2M
UTMB Clinical and Translational Science AwardUL1TR000071 · NCATS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI BRASIER, ALLAN R. · 2012 to 2014
$14.4M
MODULATION OF THE POSTBURN HYPERMETABOLIC RESPONSER01GM056687 · NIGMS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI HERNDON, DAVID N. · 1998 to 2017
$9.0M
Oxandrolone and Exercise: A potent therapy in the rehabilitation from burnsR01HD049471 · NICHD · UNIVERSITY OF TEXAS MED BR GALVESTON · PI SUMAN-VEJAS, OSCAR E. · 2006 to 2019
$5.8M
POSTDOCTORAL TRAINING IN TRAUMA &BURNST32GM008256 · NIGMS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI Celeste Campbell Finnerty, Oscar E. Suman-Vejas · 1990 to 2026
$4.0M
Effects of Chronic Catecholamine Exposure on Post-burn ScarringR01GM112936 · NIGMS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI FINNERTY, CELESTE CAMPBELL · 2015 to 2019
$1.8M
NCATS NIH HHS UL1 TR000071NCATS NIH HHS UL1 TR001439NICHD NIH HHS R01 HD049471NIGMS NIH HHS P50 GM060338NIGMS NIH HHS R01 GM056687NIGMS NIH HHS R01 GM112936NIGMS NIH HHS T32 GM008256
6 · The paper itself

Abstract

backgroundWe have reported that a 12-week exercise program is beneficial for the exercise performance of severely burned children. It is not known, however, whether the beneficial effects remain at 2 years postburn.

methodsSeverely burned children who received no long-term anabolic drugs were consented to this Institutional Review Board-approved study. Patients chose between a voluntary exercise program (EX-group) and no exercise (NoEX-group) after discharge from the acute burn unit. Peak torque per lean leg mass, maximal oxygen consumption, and percent predicted peak heart rate were assessed. In addition, body mass index percentile and lean body mass index were recorded. Both groups were compared for up to 2 years postburn using mixed multiple analysis of variance.

resultsA total of 125 patients with a mean age of 12 ± 4 years were analyzed. Demographics between the EX-group (N = 82) and NoEX-group (N = 43) were comparable. In the EX-group, peak torque per lean leg mass, percent predicted peak heart rate, and maximal oxygen consumption increased significantly with exercise (P < .01). Between discharge and 12-24 months, body mass index percentile increased significantly in the EX-Group (P < .05) but did not change in the NoEX-group. There were no significant differences between groups in body mass index percentile, lean body mass index, peak torque per lean leg mass, and maximal oxygen consumption at 24 months postburn.

conclusionExercise significantly improves the physical performance of burned children. The benefits are limited to early time points, however, and greatly narrow with further recovery time. Continued participation in exercise activities or a maintenance exercise program is recommended for exercise-induced adaptations to continue.

Indexed as

ExerciseAdolescentAge FactorsBody Mass IndexBurnsChildFemaleFollow-Up StudiesHeart RateHumansMaleMuscle StrengthOxygen ConsumptionTime FactorsTreatment Outcome

Identifiers

PMID27267551
PMCPMC4975634

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.