ArticleParasites & vectors2016
First detection of Candidatus Rickettsia barbariae in the flea Vermipsylla alakurt from north-western China.
Article in Parasites & vectors, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 25 citations in OpenAlex.
- Anaplasma spp., Coxiella, Babesia and Theileria Infections in Vermipsylla Alakurt Fleas.Acta parasitologica · 2026Article
- Research progress on emerging and important Tick-Borne pathogens.Frontiers in microbiology · 2026Review
- Identification of the PathogenVeterinary sciences · 2025Article
- Molecular Detection ofAnimals : an open access journal from MDPI · 2024Article
- Genomic characterization of an emergingEmerging microbes & infections · 2024Article
- Article
- Novel trypanosomatid species detected in Mongolian pikas (Ochotona pallasi) and their fleas in northwestern China.Parasites & vectors · 2024Article
- Detection of Rickettsia raoultii in Vermipsylla alakurt-Like Fleas of Sheep in Northwestern China.Acta parasitologica · 2024Article
- First metagenomic sequencing for the analysis of microbial community populations of adults and pupae ofFrontiers in veterinary science · 2024Article
- Tracking tick-borne diseases in Mongolian livestock using next generation sequencing (NGS).Ticks and tick-borne diseases · 2022Article
- Review
- Bartonella rochalimae, B. grahamii, B. elizabethae, and Wolbachia spp. in Fleas from Wild Rodents near the China-Kazakhstan Border.The Korean journal of parasitology · 2019Article
- Molecular detection of spotted fever group rickettsiae in ticks parasitizing pet dogs in Shihezi City, northwestern China.Experimental & applied acarology · 2019Article
- Diversity of Rickettsia species in border regions of northwestern China.Parasites & vectors · 2018Article
- Molecular evidence of Rickettsia raoultii, "Candidatus Rickettsia barbariae" and a novel Babesia genotype in marbled polecats (Vormela peregusna) at the China-Kazakhstan border.Parasites & vectors · 2018Article
- Genetic Diversity of Echinococcus granulosus Genotype G1 in Xinjiang, Northwest of China.The Korean journal of parasitology · 2018Article
- Molecular survey of ITS1 spacer and Rickettsia infection in human flea, Pulex irritans.Parasitology research · 2018Article
- Article
- First report of Rickettsia raoultii and R. slovaca in Melophagus ovinus, the sheep ked.Parasites & vectors · 2016Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVermipsylla is a genus of the family Vermipsyllidae within the order Siphonaptera of fleas. Vermipsylla alakurt is mainly distributed in alpine pastoral areas of Kazakhstan, Mongolia, China and Nepal, and infests sheep, yaks and horses, causing irritation, poor condition, anaemia and even death. However, to date, no rickettsial agents have been reported in V. alakurt.
findingsA total of 133 fleas were collected directly from the tails of three sheep flocks (n = 335) in Minfeng County, Xinjiang Uygur Autonomous Region, north-western China. Of these, 55 fleas were identified by morphological examination and molecular analysis of four loci (the ribosomal 18S and 28S rDNA genes and the mitochondrial genes cytochrome c oxidase subunit II and elongation factor 1-alpha). Eight Rickettsia-specific gene fragments originated from seven genes: the 17-kilodalton antigen gene (17-kDa), citrate synthase gene (gltA), 16S rRNA gene (rrs), outer membrane protein A gene (ompA), surface cell antigen 1 gene (sca1), PS120 protein gene (gene D), and outer membrane protein B gene (ompB, two fragments), were used to identify the species of Rickettsia in 53 fleas. The amplified products were sequenced and included in a phylogenetic analysis to verify the taxonomic identification of the rickettsial agents. Based on morphological and molecular evidence, the flea was identified as Vermipsylla alakurt. Nine samples were positive (16.98 %, 9/53) for Rickettsia spp. The phylogenetic tree revealed that the rickettsial agents found in V. alakurt cluster with Candidatus Rickettsia barbariae.
conclusionsOur study suggests that: (i) V. alakurt may serve as a carrier for Candidatus R. barbariae; and (ii) Candidatus R. barbariae, previously reported in Israel, is the eighth newly discovered validated Rickettsia species in China. This finding extends our knowledge of the distribution of Candidatus R. barbariae and the profile of carriers, which not only comprise ticks but also fleas.
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