ArticleClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2017
Incidence of Achalasia in South Australia Based on Esophageal Manometry Findings.
Article in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 5 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- Long-term outcomes of peroral endoscopic myotomy for achalasia: a systematic review and meta-analysis with median follow-up ≥ 5 years.Surgical endoscopy · 2026Pooled it
- 2024 Update to SAGES guidelines for the use of peroral endoscopic myotomy (POEM) in the treatment of achalasia.Surgical endoscopy · 2025Guideline
- Global trends in incidence and prevalence of achalasia, 1925-2021: A systematic review and meta-analysis.United European gastroenterology journal · 2024Pooled it
- Mid-Term and Long-Term Outcomes of Peroral Endoscopic Myotomy for the Treatment of Achalasia: A Systematic Review and Meta-Analysis.Digestive diseases and sciences · 2023Pooled it
- SAGES guidelines for the use of peroral endoscopic myotomy (POEM) for the treatment of achalasia.Surgical endoscopy · 2021Guideline
- Modern treatment for achalasia: endoscopic and surgical therapies.The British journal of surgery · 2026Review
- Special findings in high-resolution manometry prior to metabolic surgery: obesity as a risk factor for esophagogastric junction outflow obstruction or achalasia?Surgical endoscopy · 2026Article
- Idiopathic achalasia: unraveling the etiology and pathogenesis of an inflammatory disease.Gastroenterology report · 2026Review
- Epidemiology and practice patterns of achalasia in Taiwan: A nationwide population-based cohort study.Journal of the Chinese Medical Association : JCMA · 2025Article
- Timed barium esophagography to predict recurrent achalasia after peroral endoscopic myotomy: a retrospective study in Thailand.Clinical endoscopy · 2024Article
- Robotic Heller's myotomy using the new Hugo™ RAS system: first worldwide report.Surgical endoscopy · 2024Article
- Peroral Endoscopic Myotomy for Achalasia after Bariatric Surgery: A Case Report and Review of the Literature.Diagnostics (Basel, Switzerland) · 2023Article
- Achalasia.Nature reviews. Disease primers · 2022Review
- Type II Achalasia Is Increasing in Prevalence.Digestive diseases and sciences · 2021Article
- Establishment of a per oral endoscopic myotomy program at a rural tertiary care center.Surgical endoscopy · 2021Article
- Achalasia and esophageal cancer: a large database analysis in Japan.Journal of gastroenterology · 2021Article
- Advances in The Diagnosis and Treatment of Achalasia of The Cardia: a Review.Journal of translational internal medicine · 2021Article
- Possible new endoscopic finding in patients with achalasia: "Gingko leaf sign".Esophagus : official journal of the Japan Esophageal Society · 2020Article
- Durability of pneumatic dilation monotherapy in treatment-naive achalasia patients.BMC gastroenterology · 2019Article
- Epidemiological analysis of achalasia in Japan using a large-scale claims database.Journal of gastroenterology · 2019Article
Corrections and comments
- Commented on by
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND &
aimsAchalasia is a disorder of esophageal motility with a reported incidence of 0.5 to 1.6 per 100,000 persons per year in Europe, Asia, Canada, and America. However, estimates of incidence values have been derived predominantly from retrospective searches of databases of hospital discharge codes and personal communications with gastroenterologists, and are likely to be incorrect. We performed a cohort study based on esophageal manometry findings to determine the incidence of achalasia in South Australia.
methodsWe collected data from the Australian Bureau of Statistics on the South Australian population. Cases of achalasia diagnosed by esophageal manometry were identified from the 3 adult manometry laboratory databases in South Australia. Endoscopy reports and case notes were reviewed for correlations with diagnoses. The annual incidence of achalasia in the South Australian population was calculated for the decade 2004 to 2013. Findings were standardized to those of the European Standard Population based on age.
resultsThe annual incidence of achalasia in South Australia ranged from 2.3 to 2.8 per 100,000 persons. The mean age at diagnosis was 62.1 ± 18.1 years. The incidence of achalasia increased with age (Spearman rho, 0.95; P < .01). The age-standardized incidence ranged from 2.1 (95% CI, 1.8-2.3) to 2.5 (95% CI, 2.2-2.7).
conclusionsBased on a cohort study of esophageal manometry, we determined the incidence of achalasia in South Australia to be 2.3 to 2.8 per 100,000 persons and to increase with age. South Australia's relative geographic isolation and the population's access to manometry allowed for more accurate identification of cases than hospital code analyses, with a low probability of missed cases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.