ArticleWorld psychiatry : official journal of the World Psychiatric Association (WPA)2016
Childhood adversities and psychosis: evidence, challenges, implications.
Article in World psychiatry : official journal of the World Psychiatric Association (WPA), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
99 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- What works for whom: a systematic review of inequalities in inclusion and effectiveness of social interventions for mental ill- health.Social psychiatry and psychiatric epidemiology · 2026Pooled it
- Trauma-focused psychological interventions for psychosis: Meta-analytic evidence of differential effects on delusions and hallucinations.Psychological medicine · 2026Pooled it
- Unraveling the Concept of Childhood Adversity in Psychosis Research: A Systematic Review.Schizophrenia bulletin · 2024Pooled it
- Association Between Specific Childhood Adversities and Symptom Dimensions in People With Psychosis: Systematic Review and Meta-Analysis.Schizophrenia bulletin · 2021Pooled it
- Psychosis in children of separated parents: A systematic review and meta-analysis.European psychiatry : the journal of the Association of European Psychiatrists · 2020Pooled it
- Childhood Trauma and Neurocognition in Adults With Psychotic Disorders: A Systematic Review and Meta-analysis.Schizophrenia bulletin · 2019Pooled it
- Treatment-Resistant to Antipsychotics: A Resistance to Everything? Psychotherapy in Treatment-Resistant Schizophrenia and Nonaffective Psychosis: A 25-Year Systematic Review and Exploratory Meta-Analysis.Frontiers in psychiatry · 2019Pooled it
- Feeling out of place: a qualitative study on pathways from social adversities to early psychosis.Social psychiatry and psychiatric epidemiology · 2026Article
- Who Gets FIp? Understanding Contextual Factors in EIP Provision.Early intervention in psychiatry · 2026Article
- The longitudinal association between adverse childhood experiences and persistence of psychotic-like experiences in young people: evidence from the ALSPAC birth cohort.Psychological medicine · 2026Article
- Bullying as an Adverse Childhood Experience?-State of the Art.Children (Basel, Switzerland) · 2026Review
- Childhood Adversities and Psychosis Across Populations: Insights From the 6-Country EU-GEI Study.Schizophrenia bulletin · 2026Article
- Transdiagnostic prevention in youth mental health, Part I: rationale, shared risk factors.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- Effects of Childhood Trauma on Remembering the Past and Imagining the Future in Schizophrenia.PsyCh journal · 2025Article
- The impact of childhood trauma and cannabis use on paranoia: a structural equation model approach.Psychological medicine · 2025Observational
- Gender differences in the association between childhood trauma, clinical symptoms, and cognitive function in Chinese patients with chronic schizophrenia.Social psychiatry and psychiatric epidemiology · 2025Article
- Obsessive-compulsive symptoms as a unique presentation of complex posttraumatic stress disorder in Southeast Asia: a case report.Journal of medical case reports · 2025Article
- Belief Updating, Childhood Maltreatment, and Paranoia in Schizophrenia-Spectrum Disorders.Schizophrenia bulletin · 2025Article
- A Transdiagnostic Network Analysis of Childhood Trauma and Psychopathology.Schizophrenia bulletin · 2025Article
- Core beliefs in psychosis: a systematic review and meta-analysis.Schizophrenia (Heidelberg, Germany) · 2025Review
39 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is a substantial body of research reporting evidence of associations between various forms of childhood adversity and psychosis, across the spectrum from experiences to disorder. This has been extended, more recently, to include studies of cumulative effects, of interactions with other factors, of specific effects, and of putative biological and psychological mechanisms. In this paper we evaluate this research and highlight the remaining methodological issues and gaps that temper, but do not dismiss, conclusions about the causal role of childhood adversity. We also consider the emerging work on cumulative, synergistic, and specific effects and on mechanisms; and discuss the broader implications of this line of research for our understanding of psychosis. We conclude that the current balance of evidence is that childhood adversities - particularly exposure to multiple adversities involving hostility and threat - do, in some people, contribute to the onset of psychotic experiences and psychotic disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.