Evidence map›Paper›PMID 27262924›Full record

ReviewAdvanced drug delivery reviews2016

Advances in biosensing strategies for HIV-1 detection, diagnosis, and therapeutic monitoring.

Mark A Lifson, Mehmet Ozgun Ozen, Fatih Inci, ShuQi Wang, Hakan Inan, Murat Baday, Timothy J Henrich, Utkan Demirci

Abstract readReview
In one paragraph

Review in Advanced drug delivery reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 80 citations in OpenAlex.

  1. Article
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  4. Review
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  6. Article
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  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review-Chemical and Biological Sensors for Viral Detection.Journal of the Electrochemical Society · 2020
    Article
  14. Article
  15. Review
  16. Current Trends of Nanobiosensors for Point-of-Care Diagnostics.Journal of analytical methods in chemistry · 2019
    Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Mark A LifsonDemirci Bio-Acoustic-MEMS in Medicine (BAMM) Laboratory, Radiology Department, Canary Center at Stanford for Cancer Early Detection, Stanford University School of Medicine, Palo Alto, CA, USA.
Mehmet Ozgun OzenDemirci Bio-Acoustic-MEMS in Medicine (BAMM) Laboratory, Radiology Department, Canary Center at Stanford for Cancer Early Detection, Stanford University School of Medicine, Palo Alto, CA, USA.
Fatih InciDemirci Bio-Acoustic-MEMS in Medicine (BAMM) Laboratory, Radiology Department, Canary Center at Stanford for Cancer Early Detection, Stanford University School of Medicine, Palo Alto, CA, USA.
ShuQi WangDemirci Bio-Acoustic-MEMS in Medicine (BAMM) Laboratory, Radiology Department, Canary Center at Stanford for Cancer Early Detection, Stanford University School of Medicine, Palo Alto, CA, USA; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China; Institute for Translational Medicine, Zhejiang University, Hangzhou, China.
Hakan InanDemirci Bio-Acoustic-MEMS in Medicine (BAMM) Laboratory, Radiology Department, Canary Center at Stanford for Cancer Early Detection, Stanford University School of Medicine, Palo Alto, CA, USA; Medicine Faculty, Zirve University, Gaziantep, Turkey.
Murat BadayDemirci Bio-Acoustic-MEMS in Medicine (BAMM) Laboratory, Radiology Department, Canary Center at Stanford for Cancer Early Detection, Stanford University School of Medicine, Palo Alto, CA, USA.
Timothy J HenrichDivision of Experimental Medicine, University of California San Francisco, San Francisco, CA, USA.
Utkan DemirciDemirci Bio-Acoustic-MEMS in Medicine (BAMM) Laboratory, Radiology Department, Canary Center at Stanford for Cancer Early Detection, Stanford University School of Medicine, Palo Alto, CA, USA.
Stanford University · USUniversity of California, San Francisco · USZhejiang University · CNZirve University · TR

Funding

Rapid Fluorescence-Based Determination of Antibiotic SusceptibilityU54EB015408 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI PARRISH, JOHN A, SCHACHTER, STEVEN · 2012 to 2022
$49.2M
Platform technology for detection of cancer-associated viruses in HIV patientsR01DE024971 · NIDCR · STANFORD UNIVERSITY · PI DEMIRCI, UTKAN, KAYE, KENNETH M · 2015 to 2019
$2.1M
Novel disposable microchips for HIV-1 viral loadR01AI093282 · NIAID · STANFORD UNIVERSITY · PI DEMIRCI, UTKAN · 2012 to 2015
$1.7M
Portable Nanostructured Photonic Crystal Device for HIV-1 Viral LoadR01AI120683 · NIAID · STANFORD UNIVERSITY · PI CUNNINGHAM, BRIAN T., DEMIRCI, UTKAN · 2016 to 2019
$1.5M
A Novel Microfluidic HIV-1 Co-Culture Assay to Quantify Latent ReservoirsR21AI113117 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DEMIRCI, UTKAN, HENRICH, TIMOTHY JENSEN · 2014 to 2015
$480k
Microfluidic PCR Method to Identify and Characterize HIV-Infected Single CellsR21AI110277 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DEMIRCI, UTKAN, HENRICH, TIMOTHY JENSEN · 2014 to 2015
$474k
NIAID NIH HHS R01 AI093282NIAID NIH HHS R01 AI120683NIAID NIH HHS R21 AI110277NIAID NIH HHS R21 AI113117NIBIB NIH HHS U54 EB015408NIDCR NIH HHS R01 DE024971
6 · The paper itself

Abstract

HIV-1 is a major global epidemic that requires sophisticated clinical management. There have been remarkable efforts to develop new strategies for detecting and treating HIV-1, as it has been challenging to translate them into resource-limited settings. Significant research efforts have been recently devoted to developing point-of-care (POC) diagnostics that can monitor HIV-1 viral load with high sensitivity by leveraging micro- and nano-scale technologies. These POC devices can be applied to monitoring of antiretroviral therapy, during mother-to-child transmission, and identification of latent HIV-1 reservoirs. In this review, we discuss current challenges in HIV-1 diagnosis and therapy in resource-limited settings and present emerging technologies that aim to address these challenges using innovative solutions.

Indexed as

Anti-HIV AgentsBiosensing TechniquesHIV-1HIV InfectionsHumansMicrofluidicsNanomedicinePoint-of-Care SystemsViral LoadAnti-HIV AgentsEmerging technologiesHIV-1/AIDSMicrofluidicsNanotechnologyPoint-of-care

Identifiers

PMID27262924
PMCPMC4943868
OpenAlexW2416291062

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.