Evidence map›Paper›PMID 27262696›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2017

Sex differences in femoral deformity determined using three-dimensional assessment for osteoarthritic knees.

Tomoharu Mochizuki, Osamu Tanifuji, Yoshio Koga, Takashi Sato, Koichi Kobayashi, Katsutoshi Nishino, Satoshi Watanabe, Akihiro Ariumi, Toshihide Fujii, Hiroshi Yamagiwa and 2 more

Abstract read
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Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Article
  3. Influence of Axial Rotation Between the Femoral Neck and Ankle Joint on Kinematics in Normal Knees: A Cross-Sectional Study.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025
    Article
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  8. Variability of functional knee phenotype for coronal alignment in advanced varus knee osteoarthritis in the Japanese population.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023
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  9. Article
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  13. Review
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  16. Coronal shaft bowing of the femur affects varus inclination of the surgical transepicondylar axis in varus knee osteoarthritis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

Tomoharu MochizukiDepartment of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University, Graduate School of Medical and Dental Science, 1-757 Asahimachi-dori Chuo-ku, Niigata, Niigata, 951-8510, Japan. tommochi121710@gmail.com.
Osamu TanifujiDepartment of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University, Graduate School of Medical and Dental Science, 1-757 Asahimachi-dori Chuo-ku, Niigata, Niigata, 951-8510, Japan.
Yoshio KogaDepartment of Orthopaedic Surgery, Nioji Onsen Hospital, Niigata, Japan.
Takashi SatoDepartment of Orthopaedic Surgery, Niigata Medical Center, Niigata, Japan.
Koichi KobayashiDepartment of Health Sciences, Niigata University, School of Medicine, Niigata, Japan.
Katsutoshi NishinoNiigata Institute for Health and Sports Medicine, Niigata, Japan.
Satoshi WatanabeDepartment of Orthopaedic Surgery, Niigata Medical Center, Niigata, Japan.
Akihiro AriumiDepartment of Orthopaedic Surgery, Nagaoka Chuo General Hospital, Niigata, Japan.
Toshihide FujiiDepartment of Orthopaedic Surgery, University of Michigan, Ann Arbor, MI, USA.
Hiroshi YamagiwaDepartment of Orthopaedic Surgery, Saiseikai Niigata Daini Hospital, Niigata, Japan.
Go OmoriDepartment of Health and Sports, Faculty of Health Sciences, Niigata University of Health and Welfare, Niigata, Japan.
Naoto EndoDepartment of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University, Graduate School of Medical and Dental Science, 1-757 Asahimachi-dori Chuo-ku, Niigata, Niigata, 951-8510, Japan.
Niigata University Medical and Dental Hospital · JPNagara Medical Center · JPNiigata University of Health and Welfare · JPMisasa Onsen Hospital · JPNiigata University · JPSaiseikai Niigata Daini Hospital · JPUniversity of Michigan–Ann Arbor · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo characterize femoral deformities and determine sex differences in varus knee osteoarthritis (OA), femoral morphology and limb alignment were evaluated by using three-dimensional (3D) assessment, comparing healthy, elderly volunteers with osteoarthritic knees.

methodsA total of 178 lower limbs of 169 subjects with knee osteoarthritis (136 women, 33 men; mean age 74.9 ± 5.2 years) and 80 lower limbs of 45 healthy, elderly subjects (24 women, 21 men; mean age 65 ± 4.9 years) were examined. A 3D extremity alignment assessment system was used to examine the subjects under weight-bearing conditions on biplanar long-leg radiographs using a 3D-to-2D image registration technique. The evaluation parameters were (1) femoral bowing in the coronal plane, (2) femoral bowing in the sagittal plane, (3) femoral neck anteversion, (4) hip-knee-ankle angle, and (5) femoral torsion.

resultsHigher femoral lateral bowing and slightly higher femoral internal torsion in the proximal diaphysis were observed in women with OA compared with healthy subjects. No difference in the higher varus malalignment, no alteration in the femoral anterior bowing, and no difference in the lower femoral neck anteversion were found between men and women when comparing healthy and OA subjects.

conclusionsThe higher femoral lateral bowing and slightly higher femoral internal torsion in the proximal diaphysis in women are possibly a structural adaptation to mechanical use. The clinical significance is that the femoral deformities and the sex differences in knee OA have the potential to improve the understanding of the aetiology of primary varus knee OA. LEVEL OF EVIDENCE: IV.

Indexed as

Imaging, Three-DimensionalAgedAged, 80 and overAnkle JointBone MalalignmentFemaleFemurFemur NeckHumansKnee JointLower ExtremityMaleMiddle AgedOsteoarthritis, KneeRadiographySex FactorsFemoral deformityLower extremity alignmentOsteoarthritisSex differenceThree-dimensional assessment

Identifiers

PMID27262696
OpenAlexW2409372482

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.