Evidence map›Paper›PMID 27262287›Full record

SynthesisJournal of anesthesia2016

The comparison of adductor canal block with femoral nerve block following total knee arthroplasty: a systematic review with meta-analysis.

Xing-Qi Zhao, Nan Jiang, Fei-Fei Yuan, Lei Wang, Bin Yu

Registry-linked trialAbstract readComparative StudyMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of anesthesia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06590402 (A Pilot Study Comparing Anterior Femoral Cutaneous Nerve Blocks to Adductor Canal Blocks in Pediatric Ambulatory Knee Surgeries), which is not on this map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06590402 phase4recruitingnot on this mapstarted 2025, after this paper: background citation

A Pilot Study Comparing Anterior Femoral Cutaneous Nerve Blocks to Adductor Canal Blocks in Pediatric Ambulatory Knee Surgeries

TypeinterventionalSponsorHospital for Special Surgery, New YorkRan2025 to 2028Enrolled60ConditionsAnterior Cruciate Ligament Reconstruction, Medial Patellofemoral Ligament ReconstructionArmsBupivacaine, Dexamethasone in Adductor Canal Block, Bupivacaine, Dexamethasone in Anterior Femoral Cutaneous Nerve Block
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  16. Regional and Multimodal Analgesia to Reduce Opioid Use After Total Joint Arthroplasty: A Narrative Review.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2019
    Review
  17. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xing-Qi ZhaoDepartment of Orthopaedics and Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Nan JiangDepartment of Orthopaedics and Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Fei-Fei YuanDepartment of Neonate, Shanxi Children's Hospital, Shanxi Medical University, Taiyuan, China.
Lei WangDepartment of Orthopaedics and Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Bin YuDepartment of Orthopaedics and Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou, China. nanfanghot@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAlthough several studies have compared the clinical efficacy of an adductor canal block (ACB) to that of a femoral nerve block (FNB) for analgesia after total knee arthroplasty (TKA), disputes mainly exist in the recovery of quadriceps strength and mobilization ability between the two methods. The aim of the present study was to compare, in a systematic review and meta-analysis, the clinical efficacy of ACB with that of FNB.

methodsWe systematically searched randomized controlled trials comparing FNB with ACB for analgesia after TKA in Pubmed and the Cochrane Library from inception to April 30th 2015. There was no limitation of publication language. Trial quality was assessed using the modified Jadad scale, and eligible data were pooled for meta-analysis.

resultsFive studies of 348 patients were included. Outcomes showed that patients who received ACB had similar or better recovery of quadriceps strength and mobilization ability than those that underwent FNB. Similar efficacy was found between the two strategies regarding adductor strength, pain scores [at rest (p = 0.86), at or after knee flexion (p = 0.31)], opioid consumption (p = 0.99), opioid-associated adverse effects (p = 0.60), length of hospital stay (p = 0.42), patient satisfaction (p = 0.57), and success rate of blockade (p = 0.20).

conclusionsThe present study suggests that TKA patients who receive ACB can achieve similar or even better recovery of quadriceps strength and mobilization ability than those treated with FNB. Taken as a whole, ACB may be a better analgesia strategy after TKA at present.

Indexed as

AnalgesiaAnalgesics, OpioidArthroplasty, Replacement, KneeFemoral NerveHumansLength of StayMuscle, SkeletalMuscle StrengthNerve BlockPostoperative PainQuadriceps MuscleRandomized Controlled Trials as TopicAnalgesics, OpioidAnalgesiaFemoral adductor canal blockFemoral nerve blockMeta-analysisSystematic reviewTotal knee arthroplasty

Identifiers

PMID27262287

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.