ArticleNeuroImage2016
How reliable are MEG resting-state connectivity metrics?
Article in NeuroImage, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 215 papers, 2 of them syntheses that pooled it.
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Who cites it
215 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Tracking electrophysiological signatures of Alzheimer's disease: a systematic review of multimodal studies.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Pooled it
- Understanding brain function in vascular cognitive impairment and dementia with EEG and MEG: A systematic review.NeuroImage. Clinical · 2022Pooled it
- Age-Related Changes in Spontaneous Brain Dynamics Revealed by Resting-State Magnetoencephalography.GeroScience · 2026Article
- Differential Dynamic Reorganization of Functional Connectivity Based on Phase Synchrony and Amplitude Envelope Coupling During Propofol Sedation.Brain sciences · 2026Article
- Salience network hub dysfunction is associated with cognitive impairment in self-limited epilepsy with centrotemporal spikes: An OPM-MEG study.Epilepsia open · 2026Article
- Machine Learning Integrating SERF-MEG and VEP for Diagnosis and Differential Diagnosis of Optic Neuropathies.Bioengineering (Basel, Switzerland) · 2026Article
- The Relationship Between the Functional Integration and Topological Complexity of Human Electroencephalographic (EEG) Signals: Three Moderating Factors.Brain sciences · 2026Article
- Assessing Strengths and Limitations of Magnetoencephalography Source Imaging With Intracerebral EEG.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Article
- Appropriate Null Models for Testing the Effect of the Head Model on MEG Functional Connectivity Fingerprinting.Brain topography · 2026Article
- Decoupling of neurophysiological activity from structure mirrors global microarchitectural and neuromodulatory trends.Communications biology · 2026Article
- Distinct Resting-State Connectomes for Face and Scene Perception Predict Individual Task Performance.Human brain mapping · 2026Article
- Frequency-Resolved Cortical Functional Connectivity Across the Adult Lifespan.Human brain mapping · 2026Article
- Dynamics of brain connectivity across the Alzheimer's disease spectrum through magnetoencephalography.Scientific reports · 2026Article
- Recruitment patterns of hothubs and dark functional networks correlating activity and connectivity with magnetoencephalography.Scientific reports · 2026Article
- Frequency-resolved cortical functional connectivity across the adult lifespan.bioRxiv : the preprint server for biology · 2026Article
- Preoperative MEG reveals differential brain network characteristics in drug-resistant epilepsy patients based on vagus nerve stimulation response.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Central executive network-related neuromagnetic abnormalities in chronic and episodic migraine: a resting-state magnetoencephalography study.Frontiers in neuroscience · 2026Article
- Static and dynamic intracerebral signal analysis reveals protective networks against seizures in drug-resistant focal epilepsy.Brain communications · 2026Article
- Reliability and state-dependency of EEG connectivity, complexity and network characteristics.Scientific reports · 2025Article
155 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
MEG offers dynamic and spectral resolution for resting-state connectivity which is unavailable in fMRI. However, there are a wide range of available network estimation methods for MEG, and little in the way of existing guidance on which ones to employ. In this technical note, we investigate the extent to which many popular measures of stationary connectivity are suitable for use in resting-state MEG, localising magnetic sources with a scalar beamformer. We use as empirical criteria that network measures for individual subjects should be repeatable, and that group-level connectivity estimation shows good reproducibility. Using publically-available data from the Human Connectome Project, we test the reliability of 12 network estimation techniques against these criteria. We find that the impact of magnetic field spread or spatial leakage artefact is profound, creates a major confound for many connectivity measures, and can artificially inflate measures of consistency. Among those robust to this effect, we find poor test-retest reliability in phase- or coherence-based metrics such as the phase lag index or the imaginary part of coherency. The most consistent methods for stationary connectivity estimation over all of our tests are simple amplitude envelope correlation and partial correlation measures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.